About 1 result found for searched term "1029714-89-3" (0.12 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M40733 | Capmatinib hydrochloride | c-Met |
| INC280 hydrochloride; INCB-28060 hydrochloride | ||
| Capmatinib hydrochloride is a potent, orally active, selective, ATP-competitive c-Met kinase inhibitor that inhibits the phosphorylation of c-MET and downstream effector proteins of the c-MET pathway, with an IC50 value of 0.13 nM. In addition, Capmatinib hydrochloride In addition, Capmatinib hydrochloride can inhibit the proliferation and migration of c-Met-dependent tumor cells, and can effectively induce apoptosis (apoptosis), with anti-tumor activity. | ||
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