About 8 results found for searched term "β-Lactamase-IN-2" (0.121 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M55788 | β-Lactamase-IN-2 | Others |
| β-Lactamase-IN-2 is a beta-lactamase inhibitor. | ||
| M28436 | Zidebactam | Antibiotic |
| WCK-5107 | ||
| Zidebactam (WCK-5107) is a potent β-lactamase inhibitor. Zidebactam also is a penicillin-binding protein2 (PBP2) inhibitor with an IC50 of 0.26 μg/mL. | ||
| M28681 | Taniborbactam | Antibiotic |
| VNRX-5133 | ||
| Taniborbactam (VNRX-5133) is a reversible and selective boronic acid-containing pan-spectrum β-lactamase inhibitor with IC50s of 8-530 nM. Taniborbactam has IC50s of 30 nM, 32 nM, 42 nM, 20 nM for KPC-2, AmpC, OXA-48, and VIM-2. Taniborbactam is against Gram-negative bacteria. | ||
| M28823 | Zidebactam sodium salt | Antibiotic |
| WCK-5107 sodium salt | ||
| Zidebactam sodium salt (WCK-5107 sodium salt) is a potent β-lactamase inhibitor. Zidebactam also is a penicillin-binding protein2 (PBP2) inhibitor with an IC50 of 0.26 μg/mL. | ||
| M28890 | WCK-4234 | Antibiotic |
| WCK-4234 is a potent β-lactamase inhibitor. WCK-4234 inhibits class A, C, and D β-lactamases activity. WCK-4234 lacks direct antibacterial activity. WCK-4234 potentiates imipenem and meropenem against Enterobacteriaceae with OXA-48/OXA-181 or KPC enzymes, or with combinations of impermeability and AmpC or ESBL activity. WCK-4234 distinctively overcomes resistance mediated by OXA-type carbapenemases. | ||
| M29414 | Taniborbactam hydrochloride | Antibiotic |
| VNRX-5133 hydrochloride | ||
| Taniborbactam hydrochloride (VNRX-5133 hydrochloride) is a reversible and selective boronic acid-containing pan-spectrum β-lactamase inhibitor with IC50s of 8-530 nM. Taniborbactam hydrochloride has IC50s of 30 nM, 32 nM, 42 nM, 20 nM for KPC-2, AmpC, OXA-48, and VIM-2. Taniborbactam hydrochloride is against Gram-negative bacteria. | ||
| M29850 | IMB-XH1 | Bcl-2 |
| IMB-XH1 is an inhibitor of myeloid cell factor 1 (Mcl-1). IMB-XH1 is a non-competitive Delhi metallo-β-lactamase (NDM-1) inhibitor. The IC50s of IMB-XH1 against metallo-β-lactamases NDM-1, IMP-4, ImiS and L1 are 0.4637 μM, 3.980 μM, 0.2287 μM and 1.158 μM, respectively. | ||
| M41078 | MBL-IN-1 | Antibiotic |
| MBL-IN-1 is a β-Lactamase inhibitor, with the IC50 ranging from 0.10 to 25.85 µM. | ||
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