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ZL0590 

Cat. No. M29389

All AbMole products are for research use only, cannot be used for human consumption.

ZL0590  Structure
Size Price Availability Quantity
5mg USD 250  USD250 In stock
10mg USD 375  USD375 In stock
25mg USD 720  USD720 In stock
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Quality Control & Documentation
Biological Activity

ZL0590 is a potent, orally active BRD4 BD1-selective inhibitor with an IC50 of 90 nM for human BRD4 BD1. ZL0590 exhibits significant anti-inflammatory activities.

Chemical Information
Molecular Weight 512.55
Formula C23H27F3N4O4S
CAS Number 2230496-99-6
Form Solid
Solubility (25°C) DMSO 100 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Xiaotang Yang, et al. Int J Mol Sci. Molecular Dynamics Simulations Combined with Markov Model to Explore the Effect of Allosteric Inhibitor Binding on Bromodomain-Containing Protein 4

[2] Zhiqing Liu, et al. J Med Chem. Discovery, X-ray Crystallography, and Anti-inflammatory Activity of Bromodomain-containing Protein 4 (BRD4) BD1 Inhibitors Targeting a Distinct New Binding Site

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FHT-1015 

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  Catalog
Abmole Inhibitor Catalog




Keywords: ZL0590  supplier, Epigenetic Reader Domain, inhibitors, activators

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