All AbMole products are for research use only, cannot be used for human consumption.
YKL-05-099 is a salt-inducible kinase (SIK) inhibitor. YKL-05-099 binds to SIK1 and SIK3 with IC50s of ~10 and ~30 nM, respectively. YKL-05-099 has slightly less potent SIK2-inhibitory (IC50=40 nM).
| Molecular Weight | 600.11 |
| CAS Number | 1936529-65-5 |
| Form | Solid |
| Solubility (25°C) | DMSO ≥ 75 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[4] Marc N Wein, et al. SIKs control osteocyte responses to parathyroid hormone
| Related Salt-inducible Kinase Products |
|---|
| SIKs-IN-1
SIKs-IN-1 inhibitor. |
| MR22
MR22 is a potent pan-SIK (salt-inducible kinase) inhibitor. |
| SIK2-IN-1
SIK2-IN-1 is a potent SIK2 inhibitor over other AMPK kinases. |
| GLPG3970
GLPG3970 is a first-in-class salt-inducible kinase SIK2/SIK3 inhibitor for studies related to inflammatory and autoimmune diseases such as psoriasis. |
| YKL-06-062
YKL-06-062 is a second-generation salt-inducible kinase (SIK) inhibitor with an IC50 of 2.12 nM/1.40 nM/2.86 nM for SIK1, SIK2 and SIK3, respectively. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
