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Apafant (WEB 2086) is a potent platelet-activating factor (PAF) antagonist, it inhibits PAF binding to human PAF receptors with a Ki of 9.9 nM. WEB 2086 displays anti-inflammatory, antiangiogenic and anticancer activity. Apafant (WEB 2086) inhibits growth and proliferation of MCF-7 breast cancer cells.
| Molecular Weight | 455.96 |
| Formula | C22H22N5O2SCl |
| CAS Number | 105219-56-5 |
| Solubility (25°C) | DMSO 40 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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Products are for research use only. Not for human use. We do not sell to patients.
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