Free shipping on all orders over $ 500

Vanucizumab

Cat. No. M24682

All AbMole products are for research use only, cannot be used for human consumption.

Vanucizumab Structure
Synonym:

Anti-Human VEGFA Recombinant Antibody RO5520985

Price and Availability

For this product's availability, delivery time and price, please email [email protected] directly or click the "Inquiry Now" button below.


Quality Control & Documentation
Biological Activity

Vanucizumab is a first-in-class, bispecific IgG1-like monoclonal antibody that simultaneously blocks VEGF-A and angiopoietin-2 (Ang-2) from interacting with their receptors. Vanucizumab has antiangiogenic and anticancer effects.

Chemical Information
CAS Number 1448221-05-3
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Digna Parmar, et al. Eur J Pharmacol. Angiopoietin inhibitors: A review on targeting tumor angiogenesis

[2] Florian Heil, et al. Transl Oncol. Vanucizumab mode of action: Serial biomarkers in plasma, tumor, and skin-wound-healing biopsies

[3] Christian Klein, et al. MAbs. The use of CrossMAb technology for the generation of bi- and multispecific antibodies

Related VEGFR/PDGFR Products
SU5208 

SU5208 inhibits vascular endothelial growth factor receptor-2 (VEGFR2).

VEGFR-IN-1 

VEGFR-IN-1 is a potent angiogenesis inhibitor with IC50s of 0.02, 0.18, 0.24 7.3, and 7 µM for KDR, Flt-1, c-Kit, EGF-R, and c-Src, respectively.

(Z)-Orantinib

(Z)-Orantinib ((Z)-SU6668) is a potent, selective, orally active and ATP competitive inhibitor of Flk‐1/KDR, PDGFRβ, and FGFR1, with IC50s of 2.1, 0.008, and 1.2 µM, respectively.

(Rac)-SAR131675 

(Rac)-SAR131675 is the racemate of SAR131675.

AGL 2043 

AGL 2043 is an effective inhibitor of PDGFR (IC50=0.8 μM) and TEL-PDGFR kinases, as well as FLT3 and KIT kinases.

  Catalog
Abmole Inhibitor Catalog




Keywords: Vanucizumab, Anti-Human VEGFA Recombinant Antibody RO5520985 supplier, VEGFR/PDGFR, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.