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Revumenib (SNDX-5613)

Cat. No. M13387

All AbMole products are for research use only, cannot be used for human consumption.

Revumenib (SNDX-5613) Structure
Synonym:

SNDX5613

Size Price Availability Quantity
1mg USD 90  USD90 In stock
5mg USD 190  USD190 In stock
10mg USD 330  USD330 In stock
25mg USD 600  USD600 In stock
50mg USD 900  USD900 In stock
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Quality Control & Documentation
Biological Activity

Revumenib (SNDX-5613) is a first-in-class, effective and selective Menin-MLL binding inhibitor with Ki of 0.15 nM. Revumenib (SNDX-5613) can be used to study MLL gene rearrangement in acute leukemia, including acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML).

Chemical Information
Molecular Weight 630.82
Formula C32H47FN6O4S
CAS Number 2169919-21-3
Solubility (25°C) DMSO ≥ 20 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Huanrong Bai, et al. Expert Opin Ther Pat. Menin-MLL protein-protein interaction inhibitors: a patent review (2014-2021)

[2] Warren Fiskus, et al. Blood Cancer J. Effective Menin inhibitor-based combinations against AML with MLL rearrangement or NPM1 mutation (NPM1c)

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  Catalog
Abmole Inhibitor Catalog




Keywords: Revumenib (SNDX-5613), SNDX5613 supplier, Epigenetic Reader Domain, inhibitors, activators

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