All AbMole products are for research use only, cannot be used for human consumption.
Pregnenolone 16α-carbonitrile is a derivative of pregnendione that functions as an agonist of the rodent pregnane X receptor (PXR). pregnenolone 16α-carbonitrile is a synthetic steroid that induces expression of cytochrome P450 3A. Pregnenolone 16α-carbonitrile exhibits greater tolerance to subsequent stress injury.
| Molecular Weight | 341.49 |
| Formula | C22H31NO2 |
| CAS Number | 1434-54-4 |
| Solubility (25°C) | DMSO 20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Cytochrome P450 (e.g. CYP17) Products |
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| Musk ketone
Musk ketone is a widely used artificial fragrance. Musk ketone is also a cytochrome P450 enzyme inducer. Musk ketone shows mutagenic and comutagenic effects in Hep G2 cells and induces neural stem cell proliferation and differentiation in cerebral ischemia via activation of the PI3K/Akt signaling pathway. |
| MS-PPOH
MS-PPOH is a potent and selective cytochrome P450 (CYP) epoxygenase inhibitor. |
| (R)-Mephenytoin
(R)-Mephenytoin ((-)-Mephenytoin), the R-enantiomer of Mephenytoin. |
| (3S,5S)-Atorvastatin
(3S,5S)-Atorvastatin is a inactive enantiomer of Atorvastatin. |
| (3S,5S)-Atorvastatin sodium salt
(3S,5S)-Atorvastatin sodium salt is a pregnane X receptor (PXR) activator and the inactive enantiomer of Atorvastatin. |
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