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NKH477 (Colforsin dapropate hydrochloride) directly activates the catalytic unit of adenylate cyclase and increases intracellular cAMP. NKH477 can inhibit acute rejection of orthotopic lung allograft in rats by inhibiting proliferation in vivo.
| Molecular Weight | 546.1 |
| Formula | C27H43NO8.HCl |
| CAS Number | 138605-00-2 |
| Solubility (25°C) | Water 21.84 mg/mL |
| Storage | 4°C, dry, sealed |
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