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Myrciaphenone A

Cat. No. M17223
Myrciaphenone A Structure
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Biological Activity

Myrciaphenone A

Chemical Information
CAS Number 26089-54-3
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Carolina Rojas-Garbanzo, et al. Food Res Int. Characterization of phenolic and other polar compounds in peel and flesh of pink guava (Psidium guajava L. cv. 'Criolla') by ultra-high performance liquid chromatography with diode array and mass spectrometric detection

[2] Mamdouh Nabil Samy, et al. Chem Pharm Bull (Tokyo). Taxiphyllin 6'-O-gallate, actinidioionoside 6'-O-gallate and myricetrin 2″-O-sulfate from the leaves of Syzygium samarangense and their biological activities

[3] Mehdi Chaabi, et al. Z Naturforsch C J Biosci. Activity-guided isolation of antioxidant principles from Limoniastrum feei (Girard) Batt

[4] Marinella De Leo, et al. Planta Med. Phenolic compounds from Baseonema acuminatum leaves: isolation and antimicrobial activity

[5] M Yoshikawa, et al. Chem Pharm Bull (Tokyo). Antidiabetic principles of natural medicines. II. Aldose reductase and alpha-glucosidase inhibitors from Brazilian natural medicine, the leaves of Myrcia multiflora DC. (Myrtaceae): structures of myrciacitrins I and II and myrciaphenones A and B

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