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L-368,899 hydrochloride is a potent, selective, orally bioavailable, non-peptide oxytocin receptor antagonist, with IC50s of 8.9 nM and 26 nM for rat uterus and human uterus oxytocin receptor, respectively. L-368,899 hydrochloride used as a tocolytic agent.
| Molecular Weight | 591.23 |
| CAS Number | 160312-62-9 |
| Solubility (25°C) | DMSO 90 mg/mL Water 50 mg/mL |
| Storage | 2-8°C, dry, sealed |
[3] Eunice Hagen, et al. Autism-Like Behavior in BTBR Mice Is Improved by Electroconvulsive Therapy
| Related Oxytocin Receptor Products |
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| [Asp5]-Oxytocin
[Asp5]-Oxytocin is the first 5-position neurohypophyseal hormone analogue possessing significant biological activity. |
| (d(CH2)51, Tyr(Me)2, Thr4, Orn8, Tyr-NH29)-Vasotocin
(d(CH2)51,Tyr(Me)2,Thr4,Orn8,Tyr-NH29)-Vasotocin is an oxytocin antagonist and can be used for the research of sexual behavior. |
| (d(CH2)51, Tyr(Me)2, Orn8)-Oxytocin
(d(CH2)51,Tyr(Me)2,Orn8)-Oxytocin (OVT) is an oxytocin receptor antagonist. |
| (Val3, Pro8)-Oxytocin
(Val3,Pro8)-Oxytocin is the Gq-dependent pathway agonist. |
| (d(CH2)51, Tyr(Me)2, Thr4, Orn8, des-Gly-NH29)-Vasotocin
(d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin, an oxytocin receptor antagonist, abolishes oxytocin-enhanced inhibitory postsynaptic currents in CA1 pyramidal neurons. |
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