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Jedi2

Cat. No. M30434

All AbMole products are for research use only, cannot be used for human consumption.

Jedi2 Structure

Size	Price	Availability	Quantity
5mg	USD 95 USD95	In stock
10mg	USD 150 USD150	In stock
25mg	USD 300 USD300	In stock
50mg	USD 550 USD550	In stock

Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation

Purity: ≥99.0%
COA
MSDS

Product Information

Biological Activity

Jedi2 is a Piezo1 activator, but not a specific Piezo2 activator. Jedi2 binds to the mouse Piezo1 proteins with a Kd of 2770 μM.

Chemical Information

Molecular Weight	208.23
Formula	C10H8O3S
CAS Number	651005-90-2
Form	Solid
Solubility (25°C)	DMSO 50 mg/mL (ultrasonic)
Storage	Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month

References

[1] Weihua Yuan, et al. Curr Issues Mol Biol. The Role of the Piezo1 Mechanosensitive Channel in Heart Failure

[2] Rakhee Lohia, et al. Cell Mol Life Sci. Pharmacological activation of PIEZO1 in human red blood cells prevents Plasmodium falciparum invasion

[3] Agnes Schröder, et al. Eur J Oral Sci. Impact of PIEZO1-channel on inflammation and osteoclastogenesis mediated via periodontal ligament fibroblasts during mechanical loading

[4] Peter Kotanko, et al. FASEB Bioadv. The Piezo1 hypothesis of renal anemia

[5] Taylor R Miron, et al. Pharmacol Res. Identification of Piezo1 channels in perivascular adipose tissue (PVAT) and their potential role in vascular function

Related Piezo Channel Products
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Yoda1 Yoda 1 is a potent and selective Piezo1 agonist. Yoda 1 activates purified Piezo1 channels. Yoda 1 potently inhibits macropinocytosis induced by epidermal growth factor (EGF).

Catalog

Abmole Inhibitor Catalog

Keywords: Jedi2 supplier, Piezo Channel, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.

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