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Inobrodib

Cat. No. M21109

All AbMole products are for research use only, cannot be used for human consumption.

Inobrodib Structure
Synonym:

CCS1477; CBP-IN-1; CBP/p300-IN-4

Size Price Availability Quantity
5mg USD 180  USD180 In stock
10mg USD 320  USD320 In stock
25mg USD 690  USD690 In stock
50mg USD 960  USD960 In stock
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Quality Control & Documentation
Biological Activity

Inobrodib (CCS1477, CBP-IN-1) is an orally active, potent and selective p300/CBP inhibitor. inobrodib binds to p300 and CBP with Kd values of 1.3 and 1.7 nM and has a 170/130 fold selectivity compared to BRD4 with a Kd of 222 nM. Inobrodib (CCS1477) acts by inhibiting the expression and function of androgen receptor (AR) and by inhibiting c-Myc.

Chemical Information
Molecular Weight 534.6
Formula C30H32F2N4O3
CAS Number 2222941-37-7
Solubility (25°C) DMSO 90 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Hongrui Xu, et al. Biochem Biophys Res Commun. Structural insights revealed by the cocrystal structure of CCS1477 in complex with CBP bromodomain

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  Catalog
Abmole Inhibitor Catalog




Keywords: Inobrodib, CCS1477; CBP-IN-1; CBP/p300-IN-4 supplier, Epigenetic Reader Domain, inhibitors, activators

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