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Diaplasinin

Cat. No. M30154

All AbMole products are for research use only, cannot be used for human consumption.

Diaplasinin Structure
Synonym:

PAI-749

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Quality Control & Documentation
Biological Activity

Diaplasinin (PAI-749) is a plasminogen activator inhibitor-1 (PAI-1) inhibitor with IC50 of 295 nm. Antithrombotic efficacy.

Chemical Information
Molecular Weight 501.62
Formula C32H31N5O
CAS Number 481631-45-2
Form Solid
Solubility (25°C) DMSO 110 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] A J Lucking, et al. J Thromb Haemost. Effect of the small molecule plasminogen activator inhibitor-1 (PAI-1) inhibitor, PAI-749, in clinical models of fibrinolysis

[2] Stephen J Gardell, et al. Mol Pharmacol. Neutralization of plasminogen activator inhibitor I (PAI-1) by the synthetic antagonist PAI-749 via a dual mechanism of action

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  Catalog
Abmole Inhibitor Catalog




Keywords: Diaplasinin, PAI-749 supplier, PAI-1, inhibitors, activators

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