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Coibamide A, an N-methyl-stabilized cytotoxic depsipeptide, shows potent antiproliferative activity. Coibamide A induces autophagosome accumulation via an mTOR-independent mechanism. Coibamide A induces apoptosis. Coibamide A inhibits VEGFA/VEGFR2 expression and suppresses tumor growth in glioblastoma xenografts.
| Molecular Weight | 1287.63 |
| Formula | C65H110N10O16 |
| CAS Number | 1029227-48-2 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
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