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CFI-402257 hydrochloride is a highly selective and orally bioavailable TTK/Mps1 inhibitor with an IC50 of 1.7 nM for TTK in vitro.
| Molecular Weight | 535.04 |
| Formula | C28H31ClN6O3 |
| CAS Number | 1610677-37-6 |
| Form | Solid |
| Solubility (25°C) | DMSO 80 mg/mL Water 1 mg/mL |
| Storage | 4°C, protect from light, dry, sealed |
| Related Mps1/TTK Products |
|---|
| Mps1-IN-6
Mps1-IN-6 is a potent Mps1 inhibitor with an IC50 value of 2.596 nM. |
| RMS-07
RMS-07 is a covalent Monopolar Spindle Kinase 1 (MPS1/TTK) inhibitor, with an apparent IC50 of 13.1 nM. RMS-07 targets a poorly conserved cysteine in the kinase's hinge region. |
| CCT251455
CCT251455 is a potent and selective mitotic kinase monopolar spindle 1 (MPS1) inhibitor with an IC50 of 3 nM. |
| NMS-P715
NMS-P715 is a selective, ATP-competitive inhibitor of MPS1, with an IC50 of 182 nM. |
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