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4-Phenoxyphenyl boronic acid

Cat. No. M21545
4-Phenoxyphenyl boronic acid Structure
Synonym:

p-Phenoxyphenyl boronic acid

Size Price Availability Quantity
100mg USD 50  USD50 In stock
500mg USD 80  USD80 In stock
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Quality Control & Documentation
Biological Activity

4-phenoxy phenylboric acid can be used as a reactant.

Chemical Information
Molecular Weight 214.02
Formula C12H11BO3
CAS Number 51067-38-0
Storage RT, protect from light, dry, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Natsumi Ohishi, et al. Plants (Basel). Involvement of Auxin Biosynthesis and Transport in the Antheridium and Prothalli Formation in Lygodium japonicum

[2] Ľubica Liptkov, et al. Plant Mol Biol. Early gene expression response of barley root tip to toxic concentrations of cadmium

[3] Mayu Watanabe, et al. Biosci Biotechnol Biochem. Effect of an auxin biosynthesis inhibitor, p-phenoxyphenyl boronic acid, on auxin biosynthesis and development in rice

[4] Yusuke Kakei, et al. Plant J. Small-molecule auxin inhibitors that target YUCCA are powerful tools for studying auxin function

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