| Cat.No. | Name | Information |
|---|---|---|
| M9909 | Eltanexor | Eltanexor, also known as KPT-8602, is a second-generation exportin-1 (CRM1) inhibitor with IC50 values of 20−211 nM in 10 AML lines. |
| M21722 | Felezonexor (CBS9106) | Felezonexor (CBS9106; SL-801) is a novel reversible oral CRM1 inhibitor with CRM1 degrading activity without affecting CRM1 mRNA levels. Felezonexor is also a reversible inhibitor of XPO1, inhibits nuclear export by covalently binding to Cys528 as well as by inducing the degradation of XPO1. |
| M42175 | CRM1-IN-2 | CRM1-IN-2 is a noncovalent CRM1 inhibitor. |
| M42174 | CRM1-IN-1 | CRM1-IN-1 is a noncovalent CRM1 inhibitor. |
| M28308 | KPT-251 | KPT-251 is an orally active chromosome region maintenance 1 protein (CRM1) inhibitor. KPT-251 induces cancer cell apoptosis and shows antileukemic activity. |
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