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Peptides

Cat.No.  Name Information
M40707 Icotrokinra Icotrokinra (JNJ-77242113, JNJ-2113) is a novel, orally active IL-23R peptide antagonist for studies related to plaque psoriasis. Icotrokinra exhibits high affinity with human IL-23 receptor hIL-23R with a Kd of 7.1 pM. Icotrokinra inhibits IL-23-induced STAT3 phosphorylation in PMBCs (IC50=5.6 pM), and inhibits L-23-induced generation of IFNγ and IL-17A in picomolar levels.
M40668 SFTI-1 SFTI-1 is a head-to-tail bicyclic peptide with a disulfide bond that inhibits the serine protease trypsin with subnanomolar levels of inhibition constants. It can be used as a protease inhibitor or as a molecular grafting scaffold. In addition, by introducing a known tetrapeptide pharmacophore into the bicyclic SFTI-1, a potent ligand for melanocortin can be created.
M40634 Z-ARG-LEU-ARG-GLY-GLY-AMC acetate salt Z-ARG-LEU-ARG-GLY-GLY-AMC acetate salt is a fluorescent peptide substrate that can be used to determine the activity of UCH-L3 and USP-5.
M40619 Dentonin acetate Dentonin acetate is an amino acid peptide derived from matrix extracellular phosphoglycoprotein (MEPE) and has the ability to promote the proliferation of dental pulp stem cells (DPSCs), which can be used in studies related to endodontic restoration and osteoarthritis (OA).
M40566 Ghrelin (mouse, rat) TFA Ghrelin (mouse, rat) TFA is a gastrointestinal secretory-generated, endogenous brain-gut peptide consisting of 28 amino acids that possesses a variety of physiological functions including appetite stimulation, and is also an endogenous agonist peptide for the ghrelin (GHS) receptor.
M40562 LUNA18 LUNA18 is an orally active RAS cyclic peptide inhibitor that selectively targets, binds and inhibits Ras, thereby inhibiting Ras-dependent signaling and ultimately suppressing the proliferation of Ras-overexpressing tumor cells. It can be used in studies related to solid tumors.
M40530 LY3841136 acetate LY3841136 acetate is an amylin analog that can be used in studies related to obesity. LY3841136 acetate is an AMYR agonist.
M31385 Gonadorelin acetate Gonadorelin acetate is a decameric synthetic oligopeptide that is also a gonadotropin-releasing hormone (GnRH) agonist.
M31384 TPP-1 hydrochloride TPP-1 hydrochloride is a potent inhibitor of PD-1/PD-L1 interaction and binds specifically to PD-L1 with a Kd value of 95 nM.Can be used in tumor related studies.
M31382 Triptorelin acetate Triptorelin acetate is a synthetic decapeptide analog of luteinizing hormone-releasing hormone (LHRH) and a gonadotropin-releasing hormone (GnRH) agonist.
M31369 Beinaglutide TFA Beinaglutide TFA is a recombinant human GLP-1 (rhGLP-1) peptide and a GLP-1R agonist that can be used in studies related to obesity and non-alcoholic steatohepatitis (NASH).
M31358 [Leu15]-Gastrin I (human) [Leu15]-Gastrin I (human) is a peptide that acts via cholecystokinin (CCK) or CCK-B receptor (CCK-BR).
M31356 Iberiotoxin TFA Iberiotoxin TFA is also a selective, high-affinity blocker of the large conductance calcium-activated potassium channel (BKCa) with a Kd of approximately 1 nM.
M31353 TAT-GluA2 3Y TAT-GluA2 3Y is a GluA2-derived interfering peptide that blocks long-term depression (LTD) at glutamatergic synapses by preventing regulated endocytosis of AMPA receptors.
M31350 Rusfertide TFA Rusfertide is a peptide mimetic of hepcidin that can be used in studies related to iron deficiency anemia and true erythrocytosis (PV).
M31345 Glepaglutide Glepaglutide is a novel, long-acting glucagon-like peptide-2 (GLP-2) analog and a potent GLP-2R agonist. Glepaglutide is used in studies related to inflammatory bowel disease (IBD) and Crohn's disease.
M31341 Omiganan TFA Omiganan is a novel synthetic cationic antimicrobial peptide containing 12 amino acids, as well as a synthetic analog of indolemycin, with broad-spectrum antimicrobial and antibiofilm activity. It can be used in studies related to atopic rhinitis.
M31340 Peceleganan acetate Peceleganan (antimicrobial peptide PL-5) is a chemically synthesized, alpha-helical antimicrobial peptide containing 26 amino acid residues.
M31315 Sinapultide TFA Sinapultide is a synthetic peptide that mimics surfactant protein B (SP-B) function and can be used for the modification of synthetic phospholipid surfactants.
M31313 Pegcetacoplan Pegcetacoplan is a polyethylene glycolated peptide and an inhibitor of complement protein C3 that inhibits intravascular and extravascular hemolysis.

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