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Inhibitors
| Cat.No. | Name | Information |
|---|---|---|
| M9349 | Adenosine Dialdehyde | Adenosine Dialdehyde (ADOX) is an adenosine analog and S-adenosylmethionine-dependent methyltransferase inhibitor with an IC50 of 40 nM. |
| M9234 | Hecogenin | Hecogenin is a potent and highly selective inhibitor of UGT1A4 with an IC50 value of 1.5 μM. |
| M4798 | Tunicamycin | Tunicamycin is a mixture of homologous nucleoside antibiotics that inhibits the UDP-HexNAc: polyprenol-P HexNAc-1-P family of enzymes. |
| M3078 | Tolcapone | Tolcapone is a selective, potent and reversible of catechol-O-methyl transferase (COMT) inhibitor with Ki of 30 nM. |
| M2926 | PF-04620110 | PF-04620110 is an orally active, selective and potent diglyceride acyltransferase-1 (DGAT1) inhibitor with IC50 of 19 nM. |
| M2804 | LB42708 | LB42708 is an orally active farnesyltransferase (FTase) inhibitor with IC50 of 0.8, 1.2, and 2.0 nM toward H-ras, N-ras, and K-ras, respectively. |
| M2722 | AZD7687 | GlcNAcstatin inhibits a bacterial O-GlcNAcase (bOGA) with a Ki of 4.6 pM, inhibits human O-GlcNAcase (hOGA) with Ki of 4.4 nM, exhibits 164-fold selectivity over HexA/B. |
| M2307 | Lonafarnib | Lonafarnib (SCH 66336) is a selectively FPTase inhibitor for H-ras, K-ras-4B and N-ras with IC50 of 1.9 nM, 5.2 nM and 2.8 nM, respectively. |
| M2287 | APO866 | APO866 effectively inhibits NAMPT with IC50 of 0.09 nM. |
| M2059 | A-922500 | A-922500 is a potent and selective DGAT-1 inhibitor with IC50 values of 7 and 24 nM at human and mouse DGAT-1 respectively. |
| M1885 | Tipifarnib | Tipifarnib (R115777) is an oral farnesyltransferase inhibitor with activity in AML. |
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