Catalog

Transferase Transferase

Inhibitors

Cat.No.	Name	Information
M9234	Hecogenin	Hecogenin is a potent and highly selective inhibitor of UGT1A4 with an IC50 value of 1.5 μM.
M4798	Tunicamycin	Tunicamycin is a mixture of homologous nucleoside antibiotics that inhibits the UDP-HexNAc: polyprenol-P HexNAc-1-P family of enzymes.
M3078	Tolcapone	Tolcapone is a selective, potent and reversible of catechol-O-methyl transferase (COMT) inhibitor with K_i of 30 nM.
M2926	PF-04620110	PF-04620110 is an orally active, selective and potent diglyceride acyltransferase-1 (DGAT1) inhibitor with IC50 of 19 nM.
M2804	LB42708	LB42708 is an orally active farnesyltransferase (FTase) inhibitor with IC50 of 0.8, 1.2, and 2.0 nM toward H-ras, N-ras, and K-ras, respectively.
M2722	AZD7687	GlcNAcstatin inhibits a bacterial O-GlcNAcase (bOGA) with a K_i of 4.6 pM, inhibits human O-GlcNAcase (hOGA) with K_i of 4.4 nM, exhibits 164-fold selectivity over HexA/B.
M2307	Lonafarnib	Lonafarnib (SCH 66336) is a selectively FPTase inhibitor for H-ras, K-ras-4B and N-ras with IC50 of 1.9 nM, 5.2 nM and 2.8 nM, respectively.
M2287	APO866	APO866 effectively inhibits NAMPT with IC50 of 0.09 nM.
M2059	A-922500	A-922500 is a potent and selective DGAT-1 inhibitor with IC50 values of 7 and 24 nM at human and mouse DGAT-1 respectively.
M1885	Tipifarnib	Tipifarnib (R115777) is an oral farnesyltransferase inhibitor with activity in AML.