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Abmole Inhibitor Catalog 2017

Smo Smoothened


Cat.No.  Name Information
M9205 Glasdegib Glasdegib (PF-04449913) is a potent, orally bioavailable Smoothened (Smo) inhibitor with an IC50 of 4 nM.
M8977 MK-4101 MK-4101 is a novel SMO antagonist of the Hedgehog Pathway.
M2997 SANT-1 SANT-1 directly binds to Smoothened (Smo) receptor with Kd of 1.2 nM and inhibits Smo agonist effects with IC50 of 20 nM.
M2465 BMS-833923 BMS-833923 is an orally bioavailable Smoothened antagonist.

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