Catalog

NF-κB Nuclear factor kappa-light-chain-enhancer of activated B cells

Inhibitors

Cat.No.	Name	Information
M5371	5-Aminosalicylic acid	5-Aminosalicylic acid is a specific inhibitor of TNFα-induced IKK activity, used to treat inflammatory bowel disease.
M5232	GSK583	GSK583 is a highly potent and selective inhibitor of RIP2 kinase with an IC50 of 5 nM.
M4940	SC75741	SC75741 is a potent NF-κB inhibitor with EC50 of 200 nM.
M4005	PDTC	PDTC is a selective NF-kB inhibitor.
M3963	Bruceine A	Bruceine A, a natural quassinoid compound extracted from the dried fruits of Brucea javanica (L.) Merr., was evaluated for its antibabesial activity in vitro and in vivo.
M3930	Parthenolide	Parthenolide (PTL) is a sesquiterpene lactone isolated from feverfew and exhibits potent antitumor activity against various cancers.
M3017	Sodium 4-Aminosalicylate	Sodium 4-Aminosalicylate is an antibiotic used to treat tuberculosis via NF-κB inhibition and free radical scavenging.
M2786	JSH-23	JSH-23 is an inhibitor of NF-κB transcriptional activity with IC50 of 7.1 μM.
M2484	Caffeic Acid Phenethyl Ester	Caffeic acid phenethyl ester is a potent and specific inhibitor of NF-κB activation, and also displays antioxidant, immunomodulatory and antiinflammatory activities.
M2298	QNZ	QNZ is an inhibitor of NF-κB activation with IC50 of 11 nM.
M2197	Sulfasalazine	Sulfasalazine is an inhibitor of NF-κB activation and a procompound of the anti-inflammatory agent 5-aminosalicylic acid.