Catalog

NF-κB Nuclear factor kappa-light-chain-enhancer of activated B cells

Inhibitors

Cat.No.	Name	Information
M10545	SN50	SN50 is a cell permeable inhibitor of NF-κB translocation.
M9949	NIK SMI1	NIK SMI1 is a highly selective and potent NF-κB-inducing kinase (NIK) inhibitor.
M9825	Helenalin	Helenalin is an anti-inflammatory sesquiterpene lactone, it selectively inhibits transcription factor NF-κB by directly targeting p65.
M9645	Licochalcone D	Licochalcone D is a potent inhibitor of NF-kappaB (NF-κB) p65 with antioxidant, anti-inflammatory, anti-cancer properties.
M9456	Berbamine dihydrochloride	Berbamine dihydrochloride is a novel inhibitor of NF-κB, inhibits growth and induces apoptosis in human myeloma cells.
M8600	Urolithin B	Urolithin B is a natural product with antiproliferative and antioxidant activity.
M6180	AZD3264	AZD3264 is a novel IKK2 inhibitor.
M6179	Diethylmaleate	Diethylmaleate is the diethyl ester of maleic acid and a glutathione-depleting compound that inhibits NF-kB.
M5580	Dimethyl Fumarate	Dimethyl fumarate(DMF) is a nuclear factor (erythroid-derived)-like 2 (Nrf2) pathway activator; induces upregulation of antioxidant gene expression.
M5371	5-Aminosalicylic acid	5-Aminosalicylic acid is a specific inhibitor of TNFα-induced IKK activity, used to treat inflammatory bowel disease.
M5232	GSK583	GSK583 is a highly potent and selective inhibitor of RIP2 kinase with an IC50 of 5 nM.
M4940	SC75741	SC75741 is a potent NF-κB inhibitor with EC50 of 200 nM.
M4550	Maslinic-acid	Maslinic-acid (MA) is a Natural Triterpene, exerts a wide range of biological activities, i.e. antitumor, antidiabetic, antioxidant, cardioprotective, neuroprotective, antiparasitic and growth-stimulating.
M4067	Ginsenoside-Rg2	Ginsenoside-Rg2 is one of the major active components of ginseng, acts as a NF-κB inhibitor.
M4005	Pyrrolidinedithiocarbamate ammonium (PDTC)	Pyrrolidinedithiocarbamate ammonium (PDTC) is a selective nuclear factor-κB (NF-κB) inhibitor.
M3963	Bruceine A	Bruceine A, a natural quassinoid compound extracted from the dried fruits of Brucea javanica (L.) Merr., was evaluated for its antibabesial activity in vitro and in vivo.
M3930	Parthenolide	Parthenolide (PTL) is a sesquiterpene lactone isolated from feverfew and exhibits potent antitumor activity against various cancers.
M3161	Betulinic acid	Betulinic acid is a pentacyclic triterpene which selectively induces apoptosis in tumor cells. It acts as a new activator of NF-kB.
M3017	Sodium 4-Aminosalicylate	Sodium 4-Aminosalicylate is an antibiotic used to treat tuberculosis via NF-κB inhibition and free radical scavenging.
M2844	Methylthiouracil	Methylthiouracil is an antithyroid preparation, Methylthiouracil suppresses the production TNF-α and IL-6, and the activation of NF-κB and ERK1/2.
M2786	JSH-23	JSH-23 is an inhibitor of NF-κB transcriptional activity with IC50 of 7.1 μM.
M2484	Caffeic Acid Phenethyl Ester	Caffeic acid phenethyl ester is a potent and specific inhibitor of NF-κB activation, and also displays antioxidant, immunomodulatory and antiinflammatory activities.
M2298	QNZ	QNZ is an inhibitor of NF-κB activation with IC50 of 11 nM.
M2197	Sulfasalazine	Sulfasalazine is an inhibitor of NF-κB activation and a procompound of the anti-inflammatory agent 5-aminosalicylic acid.

Signaling Pathways

Product Type

NF-κB Nuclear factor kappa-light-chain-enhancer of activated B cells

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