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  Catalog
Abmole Inhibitor Catalog 2017

NF-κB Nuclear factor kappa-light-chain-enhancer of activated B cells

Inhibitors

Cat.No.  Name Information
M5580 Dimethyl Fumarate Dimethyl fumarate(DMF) is a nuclear factor (erythroid-derived)-like 2 (Nrf2) pathway activator; induces upregulation of antioxidant gene expression.
M5371 5-Aminosalicylic acid 5-Aminosalicylic acid is a specific inhibitor of TNFα-induced IKK activity, used to treat inflammatory bowel disease.
M5232 GSK583 GSK583 is a highly potent and selective inhibitor of RIP2 kinase with an IC50 of 5 nM.
M4940 SC75741 SC75741 is a potent NF-κB inhibitor with EC50 of 200 nM.
M4005 PDTC PDTC is a selective NF-kB inhibitor.
M3963 Bruceine A Bruceine A, a natural quassinoid compound extracted from the dried fruits of Brucea javanica (L.) Merr., was evaluated for its antibabesial activity in vitro and in vivo.
M3930 Parthenolide Parthenolide (PTL) is a sesquiterpene lactone isolated from feverfew and exhibits potent antitumor activity against various cancers.
M3017 Sodium 4-Aminosalicylate Sodium 4-Aminosalicylate is an antibiotic used to treat tuberculosis via NF-κB inhibition and free radical scavenging.
M2786 JSH-23 JSH-23 is an inhibitor of NF-κB transcriptional activity with IC50 of 7.1 μM.
M2484 Caffeic Acid Phenethyl Ester Caffeic acid phenethyl ester is a potent and specific inhibitor of NF-κB activation, and also displays antioxidant, immunomodulatory and antiinflammatory activities.
M2298 QNZ QNZ is an inhibitor of NF-κB activation with IC50 of 11 nM.
M2197 Sulfasalazine Sulfasalazine is an inhibitor of NF-κB activation and a procompound of the anti-inflammatory agent 5-aminosalicylic acid.

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