|M10666||CW069||CW069 is an allosteric inhibitor of HSET with IC50 of 75 μM, it showed marked activity against HSET in vitro.|
|M9174||ARQ 621||ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor.|
|M8930||EMD534085||EMD534085 is a potent and selective inhibitor of the mitotic kinesin-5 with an IC50 of 8 nM.|
|M8918||BAY 1217389||BAY 1217389 is a potent, and selective inhibitor of the monopolar spindle 1 (MPS1) kinase with an IC50 value less than 10 nM.|
|M7876||K-858||Eg5 is a key protein involved in the formation of bipolar spindles.|
|M5230||Monastrol||Monastrol is a cell-permeable small molecule inhibitor of kinesin-5(KIF11) which is essential for maintaining separation of the half-spindles.|
|M3672||AZD4877||AZD4877 is a synthetic kinesin spindle protein (KSP) inhibitor with potential antineoplastic activity.|
|M3216||ARRY-520||ARRY-520 is a potent and selective kinesin spindle protein (KSP) inhibitor with an IC50 of 15 nM for A2780, CP70 and 01-28 cell lines in vitro.|
|M2868||MPI-0479605||MPI-0479605 is an ATP competitive and selective inhibitor of mitotic kinase Mps1 with IC50 of 1.8 nM, >40-fold selectivity over other kinases.|
|M2171||GSK923295||GSK923295 is an allosteric inhibitor of CENP-E with Ki value of 3.2 nM.|
|M2128||AZ3146||AZ3146 is a potent and selective monopolar spindle 1 (Mps1) kinase inhibitor with IC50 of 35 nM.|
|M1983||SB-743921||SB-743921 is a highly potent and active KSP inhibitor with a Ki of 0.1 nM for KSP (Eg5).|
|M1786||Ispinesib||Ispinesib (SB 715992) is the first potent, highly specific small-molecule inhibitor of kinesin spindle protein (KSP) with an IC50 of 4.1 nM.|
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