Catalog

Kinesin Kinesin

Inhibitors

Cat.No.	Name	Information
M9174	ARQ 621	ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor.
M8930	EMD534085	EMD534085 is a potent and selective inhibitor of the mitotic kinesin-5 with an IC50 of 8 nM.
M8918	BAY 1217389	BAY 1217389 is a potent, and selective inhibitor of the monopolar spindle 1 (MPS1) kinase with an IC50 value less than 10 nM.
M7876	K-858	Eg5 is a key protein involved in the formation of bipolar spindles.
M5230	Monastrol	Monastrol is a cell-permeable small molecule inhibitor of kinesin-5(KIF11) which is essential for maintaining separation of the half-spindles.
M3672	AZD4877	AZD4877 is a synthetic kinesin spindle protein (KSP) inhibitor with potential antineoplastic activity.
M3216	ARRY-520	ARRY-520 is a potent and selective kinesin spindle protein (KSP) inhibitor with an IC50 of 15 nM for A2780, CP70 and 01-28 cell lines in vitro.
M2868	MPI-0479605	MPI-0479605 is an ATP competitive and selective inhibitor of mitotic kinase Mps1 with IC50 of 1.8 nM, >40-fold selectivity over other kinases.
M2171	GSK923295	GSK923295 is an allosteric inhibitor of CENP-E with Ki value of 3.2 nM.
M2128	AZ3146	AZ3146 is a potent and selective monopolar spindle 1 (Mps1) kinase inhibitor with IC50 of 35 nM.
M1983	SB-743921	SB-743921 is a highly potent and active KSP inhibitor with a Ki of 0.1 nM for KSP (Eg5).
M1786	Ispinesib	Ispinesib (SB 715992) is the first potent, highly specific small-molecule inhibitor of kinesin spindle protein (KSP) with an IC50 of 4.1 nM.