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Abmole Inhibitor Catalog 2017

Kinesin Kinesin

Inhibitors

Cat.No.  Name Information
M5230 Monastrol Monastrol is a cell-permeable small molecule inhibitor of kinesin-5(KIF11) which is essential for maintaining separation of the half-spindles.
M3672 AZD4877 AZD4877 is a synthetic kinesin spindle protein (KSP) inhibitor with potential antineoplastic activity.
M3216 ARRY-520 ARRY-520 is a potent and selective kinesin spindle protein (KSP) inhibitor with an IC50 of 15 nM for A2780, CP70 and 01-28 cell lines in vitro.
M2868 MPI-0479605 MPI-0479605 is an ATP competitive and selective inhibitor of mitotic kinase Mps1 with IC50 of 1.8 nM, >40-fold selectivity over other kinases.
M2171 GSK923295 GSK923295 is an allosteric inhibitor of CENP-E with Ki value of 3.2 nM.
M2128 AZ3146 AZ3146 is a potent and selective monopolar spindle 1 (Mps1) kinase inhibitor with IC50 of 35 nM.
M1983 SB-743921 SB-743921 is a highly potent and active KSP inhibitor with a Ki of 0.1 nM for KSP (Eg5).
M1786 Ispinesib Ispinesib (SB 715992) is the first potent, highly specific small-molecule inhibitor of kinesin spindle protein (KSP) with an IC50 of 4.1 nM.


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