Catalog

Histone Methyltransferase Histone methyltransferase

Inhibitors

Cat.No.	Name	Information
M5414	Amoxicillin trihydrate	Amodiaquine dihydrochloride dihydrate is a histamine N-methyltransferase inhibitor, used as an antimalarial and anti-inflammatory agent.
M5412	Amodiaquin dihydrochloride dihydrate	Amodiaquine is a potent, non-competitive inhibitor of histamine N-methyl transferase in human erythrocytes, also used as an antimalarial and anti-inflammatory agent.
M5186	CPI-360	CPI-360 is a potent, selective,and SAM-competitive EZH1 inhibitor with IC50 of 102.3 nM.
M5163	SGC707	SGC707 is a potent, selective and cell-active allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3) with IC50 and Kd of 31 nM and 53 nM, respectively.
M5128	PFI-2	PFI-2 is a potent, selective, and cell-active lysine methyltransferase SETD7 inhibitor with Ki (app) and IC50 of 0.33 nM and 2 nM, 1000-fold selectivity over other methyltransferases and other non-epigenetic targets.
M2358	3-Deazaneplanocin A	3-deazaneplanocin A (DZNeP), an analog of adenosine, is a competitive inhibitor of S-adenosylhomocysteine hydrolase with K_i of 50 pM.
M2334	EPZ004777	EPZ004777 is a potent, selective, small-molecule inhibitor of DOT1L with IC50 of 0.4 nM.
M2179	EPZ-5676	EPZ-5676 is a potent and selective aminonucleoside inhibitor of DOT1L histone methyltransferase.
M2024	BIX 01294	BIX 01294 is a potent inhitor of G9a histone methyltransferase with IC50 of 2.7 μM.