|M6177||SGC2085||SGC2085 is a potent and selective Coactivator Associated Arginine Methyltransferase 1 (CARM1) inhibitor with an IC50 value of 50 nM and >100-fold selective over other PRMTs.|
|M6142||XY1||XY1 is a very close analogue of SGC707 (a potent, selective, and non-competitive inhibitor of PRMT3 with IC50 of 31 nM), but XY1 is completely inactive.|
|M5412||Amodiaquin dihydrochloride dihydrate||Amodiaquine is a potent, non-competitive inhibitor of histamine N-methyl transferase in human erythrocytes, also used as an antimalarial and anti-inflammatory agent.|
|M5186||CPI-360||CPI-360 is a potent, selective,and SAM-competitive EZH1 inhibitor with IC50 of 102.3 nM.|
|M5163||SGC707||SGC707 is a potent, selective and cell-active allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3) with IC50 and Kd of 31 nM and 53 nM, respectively.|
|M5128||PFI-2||PFI-2 is a potent, selective, and cell-active lysine methyltransferase SETD7 inhibitor with Ki (app) and IC50 of 0.33 nM and 2 nM, 1000-fold selectivity over other methyltransferases and other non-epigenetic targets.|
|M2358||3-Deazaneplanocin A||3-deazaneplanocin A (DZNeP), an analog of adenosine, is a competitive inhibitor of S-adenosylhomocysteine hydrolase with Ki of 50 pM.|
|M2334||EPZ004777||EPZ004777 is a potent, selective, small-molecule inhibitor of DOT1L with IC50 of 0.4 nM.|
|M2179||EPZ-5676||EPZ-5676 is a potent and selective aminonucleoside inhibitor of DOT1L histone methyltransferase.|
|M2024||BIX 01294||BIX 01294 is a potent inhitor of G9a histone methyltransferase with IC50 of 2.7 μM.|
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