|M6089||XMD8-92||XMD8-92 is a potent and selective BMK1/ERK5 inhibitor with Kd of 80 nM.|
|M5345||VRT752271||VRT752271 (BVD-523, Ulixertinib) is a potent and reversible ERK1/ERK2 inhibitor with IC50 of <0.3 nM for ERK2. Phase 1.|
|M5248||DEL-22379||DEL-22379 is a water-soluble ERK dimerization inhibitor with IC50 of ∼0.5 μM.|
|M4819||XMD17-109||XMD17-109 is a novel, specific inhibitor of ERK-5 with an EC50 value of 4.2 μM in HEK293 cells.|
|M3668||GDC-0994||GDC-0994 is a potent, orally available ERK inhibitor with IC50 1.1 nM and 0.3 nM, respectively.|
|M3642||FR 180204||FR 180204 is an ATP-competitive, selective ERK inhibitor with Ki of 0.31 μM and 0.14 μM for ERK1 And ERK2, respectively.|
|M2084||SCH772984||SCH772984 is a novel and selective inhibitor of ERK1/2 with IC50 of 4 nM and 1 nM, respectively.|
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