|M9300||AG 126||AG 126 is a cell-permeable inhibitor of lipopolysaccharide (LPS)-induced synthesis of tumor necrosis factor-α and nitric oxide in murine peritoneal macrophages.|
|M9108||AZD-0364||AZD-0364 is a potent and selective ERK2 inhibitor with an IC50 of 0.6 nM.|
|M6266||Pluripotin||Pluripotin (SC1) is a dual inhibitor of extracellular signal-regulated kinase 1 (ERK1, MAPK3) and RasGAP. Maintains embryonic stem cell (ESC) self-renewal.|
|M6235||VX-11e||VX-11e is a potent, selective, and orally bioavailable ERK2 inhibitor with Ki of <2 nM, over 200-fold selective over other kinases tested.|
|M6089||XMD8-92||XMD8-92 is a potent and selective BMK1/ERK5 inhibitor with Kd of 80 nM.|
|M5345||VRT752271||VRT752271 (BVD-523, Ulixertinib) is a potent and reversible ERK1/ERK2 inhibitor with IC50 of <0.3 nM for ERK2.|
|M5340||Tauroursodeoxycholate Sodium||Sodium Tauroursodeoxycholate (TUDC) is a water soluble bile salt, used for the treatment of gallstones and liver cirrhosis.|
|M5248||DEL-22379||DEL-22379 is a water-soluble ERK dimerization inhibitor with IC50 of ∼0.5 μM.|
|M5158||Tauroursodeoxycholic acid||Tauroursodeoxycholic acid (TUDCA) is an ambiphilic bile acid.|
|M4819||XMD17-109||XMD17-109 (ERK5-IN-1) is a novel, specific inhibitor of ERK-5 with an EC50 value of 4.2 μM in HEK293 cells.|
|M4662||Nitidine chloride||Nitidine chloride is a benzophenanthridine alkaloid found in species of the genus Zanthoxylum with anti-malarial activity.|
|M3668||GDC-0994||GDC-0994 is a potent, orally available ERK inhibitor with IC50 1.1 nM and 0.3 nM, respectively.|
|M3642||FR 180204||FR 180204 is an ATP-competitive, selective ERK inhibitor with Ki of 0.31 μM and 0.14 μM for ERK1 And ERK2, respectively.|
|M2084||SCH772984||SCH772984 is a novel and selective inhibitor of ERK1/2 with IC50 of 4 nM and 1 nM, respectively.|
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