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Metabolite/Endogenous Metabolite Metabolite/Endogenous Metabolite

Inhibitor

Cat.No.  Name Information
M10346 Glutamic acid (L-Glutamic acid) L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA).
M5450 Benzyl alcohol Benzyl alcohol is used as a local anesthetic. Also, it is used in the manufacture of other benzyl compounds, as a pharmaceutic aid, and in perfumery and flavoring.
M5436 Azelaic acid Azelaic acid is an unsaturated fatty acid derived from plant seeds, which can also be derived from ozonolysis of oleic acid, and has antimicrobial and antioxidant activity.
M5388 Ademetionine Ademetionine(S-adenosyl-l-methionine; SAMe) is a naturally-occurring substance which is a major source of methyl groups in the brain.
M5370 5,5-Dimethyloxazolidine-2,4-dione Dimethadione is an anticonvulsant that is the active metabolite of trimethadione.
M5362 3-Methylsalicylic acid 3-Methylsalicylic acid is a salicylic acid derivative that acts on human plasma and has significant fibrinolytic activity by activating the fibrinolytic system.
M5066 N-Desethyl Sunitinib N-desethyl sunitinib is a major and pharmacologically active metabolite of sunitinib, which is potent, ATP-competitive VEGFR, PDGFRβ and KIT inhibitor (Ki values are 2, 9, 17, 8 and 4 nM for VEGFR -1, -2, -3, PDGFRβ and KIT respectively).
M4943 3,4,5-Trimethoxyphenylacetic acid Cell suspensions did not release carbon dioxide from 3,4-[methoxyl-14C]dihydroxy-5-methoxyphenylacetate but accumulated 1 mol of methanol per mol of 3,4,5-trimethoxyphenylacetate oxidized.
M4842 Cotinine Cotinine is an alkaloid found in tobacco and is also the predominant metabolite of nicotine.
M4781 Homovanillic-acid Homovanillic acid is a dopamine metabolite associated with aromatic amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and adiponectin reductase deficiency.
M4730 Diosbulbin-B Diosbulbin B is derived from D. Bulbifera L. Diterpene lactone isolated from the diterpene lactone has antitumor activity. Diosbulbin B can cause liver injury.
M4729 α-Cyperone Alpha-cyperone (α -cyperone) is associated with down-regulated expression of COX-2, IL-6, NCK-2, Cdc42, and Rac1, thereby reducing the inflammatory response.*The compound is unstable in solutions, freshly prepared is recommended
M4696 5-HTP 5-Hydroxytryptophan is a metabolite of tryptophan, a direct precursor of 5-hydroxytryptophan (5-HT), and a substrate of aromatic amino acid decarboxylase.
M4603 D-(-)-Quinic-acid D-(-)-Quinic-acid is a cyclohexanecarboxylic acid.
M4602 p-Coumaric-acid P -Coumaric acid is an isomer of cinnamic acid, which has anti-tumor and anti-mutagenic activities.
M4587 β-Carotene Beta-carotene (Provitamin A) is A class of carotenoid compounds that are naturally occurring precursors of vitamin A. Beta-carotene is a ROS regulator with antioxidant and anti-inflammatory activities. β -carotene can be either an antioxidant or a pro-oxidant, depending on its intrinsic properties and the REDOX potential of the biological environment it acts on. β -carotene can induce apoptosis of breast cancer cells and has anti-cancer activity.
M4561 Sodium-Demethylcantharidate Sodium Demethylcantharidate is an endogenous metabolite.
M4499 Crocin-I Crocin I (Crocin I) is a nutritional supplement isolated from the stigmas of Crocus sativus. It has anti-inflammatory, anticancer, antidepressant and anticonvulsant effects.
M4310 Lucidenic-acid-LM1 Lucidenic acid LM1 is a natural terpene isolated from Ganoderma lucidum.
M4277 Hydroxytyrosol Hydroxytyrosol (DOPET) is a phenolic compound derived from the olive tree and its leaves that has antioxidant, anti-atherosclerotic, anti-thrombotic, antibacterial, anti-inflammatory, and anti-tumor properties.
M4232 Ginkgolide-B Ginkgolide B (BN-52021), a terpenoid, is one of the important active substances in ginkgo biloba leaves.




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