Free shipping on all orders over $ 500

Hydroxytyrosol

Cat. No. M4277
Hydroxytyrosol Structure
Size Price Availability Quantity
10mg USD 48  USD48 In stock
50mg USD 92  USD92 In stock
100mg USD 150  USD150 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Hydroxytyrosol (DOPET) is a phenolic compound derived from the olive tree and its leaves that has antioxidant, anti-atherosclerotic, anti-thrombotic, antibacterial, anti-inflammatory, and anti-tumor properties.

Chemical Information
Molecular Weight 154.16
CAS Number 10597-60-1
Solubility (25°C) DMSO ≥ 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Matteo Bertelli, et al. Hydroxytyrosol: A natural compound with promising pharmacological activities

[2] Ana Karković Marković, et al. Hydroxytyrosol, Tyrosol and Derivatives and Their Potential Effects on Human Health

[3] Maria Carmen Lopez de Las Hazas, et al. Hydroxytyrosol: Emerging Trends in Potential Therapeutic Applications

[4] Mara Robles-Almazan, et al. Hydroxytyrosol: Bioavailability, toxicity, and clinical applications

[5] Francisca Echeverra, et al. Hydroxytyrosol and Cytoprotection: A Projection for Clinical Interventions

Related Metabolite/Endogenous Metabolite Products
2,3-Dihydroxyisovaleric acid

2,3-Dihydroxyisovaleric acid is a natural metabolite of the branched-chain amino acid leucine. It acts by activating the mTOR signaling pathway to promote the synthesis of new muscle proteins and reduce the breakdown of existing proteins.

Ursocholic acid

Ursocholic acid is a bile acid found predominantly in bile of mammals, which can be transformed into deoxycholic acid by the intestinal microflora in mice.

5β-Cholanic acid

5β-Cholanic acid can be used for 5β-Cholanic acid derivatives synthesis.

D-Thyroxine

D-Thyroxine is a thyroid hormone that can inhibit TSH secretion. D-Thyroxine can be used for the research of hypercholesterolemia.

Allolithocholic acid

Allolithocholic acid is a steroid acid could found in normal serum and feces. Allolithocholic acid facilitates excretion, absorption, and transport of fats and sterols in the intestine and liver.

  Catalog
Abmole Inhibitor Catalog




Keywords: Hydroxytyrosol supplier, Metabolite/Endogenous Metabolite, inhibitors, activators


Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.