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Abmole Inhibitor Catalog 2017

Anti-infection Anti-infection


Cat.No.  Name Information
M10473 MK-3118 MK-3118 is a novel glucan synthase inhibitor with activity against many echinocandin-resistant strains of Candida due to differential avidity for the target site compared to echinocandins.
M10444 Oteseconazole Oteseconazole (VT-1161) is an orally active anti-fungal agent, potently binds to and inhibits Candida albicans CYP51 (Kd <39 nM).
M10421 Sodium citrate (dihydrate) Sodium citrate dehydrate is an anticoagulant and also used as a buffer and food preservatives.
M10360 Arteannuin B Arteannuin B co-occurs with artemisinin, Arteannuin B shows anti-SARS-CoV-2 potential with an EC50 of 10.28 μM.
M10359 Dihydroartemisinic acid Dihydroartemisinic acid is a natural product from Artemisia annua and the main direct precursor of artemisinin, which is a medicinal herb that is widely used to treat Malaria.
M10339 Fexinidazole Fexinidazole (also known as Hoe-239) is an orally active, potent antiparasitic agent.
M10241 Polymyxin B nonapeptide TFA Polymyxin B nonapeptide TFA is a cyclic peptide from the naturally occurring peptide polymyxin B, it can increase the permeability of the outer membrane of Gram-negative bacteria toward hydrophobic antibiotics.
M10232 Cefotaxime Cefotaxime is an inhibitor of penicillin binding protein.
M10178 Cefoperazone sodium Cefoperazone sodium is a semi-synthetic, broad-spectrum, beta-lactamase resistant antibiotic with bactericidal activity.
M10163 Baloxavir marboxil Baloxavir marboxil is a novel cap-dependent endonuclease inhibitor for the treatment of influenza A and B virus infections.
M10148 Juglone Juglone is a natural naphthoquinone found in the black walnut (Juglans regia) shows antimicrobial activity.
M10127 Azathramycin Azathramycin is an antibiotic, binding to the 50S subunit of the bacterial ribosome, and thus inhibits translation of mRNA.
M10084 AMY-101 acetate AMY-101 acetate is a peptidic inhibitor of the central complement component C3 (KD = 0.5 nM).
M10082 Amodiaquine Amodiaquine is a 4-aminoquinoline compound related to chloroquine, used as an antimalarial and anti-inflammatory agent.
M10031 Lysozyme (from egg white) Lysozyme (from egg white) is a bactericidal enzyme present in chicken eggs, and it lyses gram-positive bacteria.
M10028 Phe-Arg-β-naphthylamide 2HCl Phe-Arg-β-naphthylamide 2HCl is an efflux pump inhibitor (EPI), it acts on the major multidrug resistance efflux transporters of Gram-negative bacteria.
M9963 Allicin Allicin has highly potent antimicrobial activity, and inhibits growth of a variety of microorganisms, among them antibiotic-resistant strains.
M9955 LL-37 (Human) Antibacterial Protein LL-37 (human) is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity.
M9847 N-(Ketocaproyl)-D,L-homoserine lactone N-(Ketocaproyl)-D,L-homoserine lactone is a natural, active ligand of LuxR. N-(Ketocaproyl)-D,L-homoserine lactone is also a quorum sensing (QS) autoinducer.
M9845 PBP10 TFA salt PBP10 is a 10-AA peptide with rhodamine conjugated at its N terminus, exerts bactericidal activity against gram-positive and gram-negative bacteria and limits microbial-induced inflammatory effects.
M9843 Triclocarban Triclocarban is an antimicrobial agent.
M9829 NGI-1 NGI-1 (ML414) is an inhibitor of Asparagine (N)-linked glycoslysation, which inhibits the oligosaccharyltransferase, preventing the attachment to the protein.
M9795 8-Epidiosbulbin E acetate 8-Epidiosbulbin E acetate is abundant in Dioscorea bulbifera L. , it exhibits broad-spectrum plasmid-curing activity against multidrug-resistant (MDR) bacteria.
M9775 Fluralaner Fluralaner inhibits γ-aminobutyric acid (GABA)-gated chloride channels (GABACls) and l-glutamate-gated chloride channels (GluCls).
M9772 CHIR-090 CHIR-090 is a very potent and selective LpxC inhibitor, it is also a two-step slow, tight-binding inhibitor of E. coli LpxC with Ki = 4.0 nM.
M9756 Pocapavir Pocapavir (also known as SCH-48973 and V-073) is a potent, selective anti-enterovirus agent.
M9728 Fluensulfone Fluensulfone is a new nematicide for chemical control of plant parasitic nematodes.
M9721 Qstatin Qstatin is a selective inhibitor of quorum sensing (QS) in vibrio species.
M9694 Chlorhexidine Chlorhexidine is a disinfectant and topical anti-infective agent.
M9641 PLpro inhibitor PLpro inhibitor is a potent papain-like protease (PLpro) inhibitor with IC50 of 2.6 μM.
M9612 XP-59 XP-59 is a potent inhibitor of the SARS-CoV Mpro, with a Ki of 0.1 μM.
M9605 Molnupiravir (EIDD-2801) Molnupiravir (EIDD-2801) is an orally bioavailable form of a highly potent ribonucleoside analog that inhibits the replication of multiple RNA viruses including SARS-CoV-2, the causative agent of COVID-19.
M9603 GS-441524 GS-441524 is a potent inhibitor of feline infectious peritonitis virus (FIPV) with EC50 of 0.78 μM.
M9589 Rifamycin sodium Rifamycin sodium belongs to the family of ansamycin antibiotics, it is an antibiotic that inhibits bacterial DNA-dependent RNA polymerase.
M9585 MAC-545496 MAC-545496 is potent GraR inhibitor (glycopeptide-resistance-associated protein R), reverses β-lactam resistance in the community-acquired MRSA USA300 strain.
M9538 Nisin Nisin is a bacteriocin produced by a group of Gram-positive bacteria that belongs to Lactococcus and Streptococcus species.
M9503 E1210 E1210 (APX001A) is the first-in-class inhibitor of the fungal protein Gwt1 (GPI-anchored wall transfer protein 1) in the glycosylphosphatidylinositol (GPI) biosynthesis pathway.
M9501 AN2718 AN2718 is a novel boron-containing small molecule that inhibits an essential protein synthesis enzyme, leucyl-transfer RNA synthetase, or LeuRS.
M9500 Tavaborole Tavaborole, also known as AN-2690 is an antifungal agent with activity against Trichophyton species.
M9462 Pyronaridine tetraphosphate Pyronaridine tetraphosphate is a Mannich base anti-malarial with demonstrated efficacy against compound.
M9461 Oxyclozanide Oxyclozanide is a salicylanilide anthelmintic compound, which acts by uncoupling oxidative phosphorylation in flukes.
M9460 Tilorone dihydrochloride Tilorone dihydrochloride is an orally active interferon inducer, used as an antiviral compound.
M9452 Sulfaphenazole Sulfaphenazole is an inhibitor of CYP2C9, which blocks atherogenic and pro-inflammatory effects of linoleic acid mediated by CYP2C9.
M9441 GSK656 HCl GSK656 is a potent Mtb LeuRS inhibitor, shows potent inhibition of Mtb LeuRS (IC50 = 0.20 μM) and in vitro antitubercular activity (Mtb H37Rv MIC = 0.08 μM).
M9431 Aureobasidin A Aureobasidin A (AbA) is a cyclic ester peptide antibiotics which derived from filamentous fungi, and it has strong antifungal ability.
M9430 Phleomycin Phleomycin is a glycopeptide antibiotic.
M9352 Gramicidin Gramicidin is an antimicrobial peptide assembling as channels in membranes and increasing their permeability towards cations.
M9335 Cefazolin Cefazolin is a semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis.
M9334 Vancomycin Vancomycin is an antibiotic for the treatment of bacterial infections.
M9321 Nourseothricin sulfate Nourseothricin is a broad-spectrum antibiotic derived from Streptomyces noursei.

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