Inhibitors
Cat.No. | Name | Information |
---|---|---|
M9847 | N-(Ketocaproyl)-D,L-homoserine lactone | N-(Ketocaproyl)-D,L-homoserine lactone is a natural, active ligand of LuxR. N-(Ketocaproyl)-D,L-homoserine lactone is also a quorum sensing (QS) autoinducer. |
M9845 | PBP10 TFA salt | PBP10 is a 10-AA peptide with rhodamine conjugated at its N terminus, exerts bactericidal activity against gram-positive and gram-negative bacteria and limits microbial-induced inflammatory effects. |
M9843 | Triclocarban | Triclocarban is an antimicrobial agent. |
M9829 | NGI-1 | NGI-1 (ML414) is an inhibitor of Asparagine (N)-linked glycoslysation, which inhibits the oligosaccharyltransferase, preventing the attachment to the protein. |
M9795 | 8-Epidiosbulbin E acetate | 8-Epidiosbulbin E acetate is abundant in Dioscorea bulbifera L. , it exhibits broad-spectrum plasmid-curing activity against multidrug-resistant (MDR) bacteria. |
M9775 | Fluralaner | Fluralaner inhibits γ-aminobutyric acid (GABA)-gated chloride channels (GABACls) and l-glutamate-gated chloride channels (GluCls). |
M9772 | CHIR-090 | CHIR-090 is a very potent and selective LpxC inhibitor, it is also a two-step slow, tight-binding inhibitor of E. coli LpxC with Ki = 4.0 nM. |
M9756 | Pocapavir | Pocapavir (also known as SCH-48973 and V-073) is a potent, selective anti-enterovirus agent. |
M9728 | Fluensulfone | Fluensulfone is a new nematicide for chemical control of plant parasitic nematodes. |
M9721 | Qstatin | Qstatin is a selective inhibitor of quorum sensing (QS) in vibrio species. |
M9694 | Chlorhexidine | Chlorhexidine is a disinfectant and topical anti-infective agent. |
M9641 | PLpro inhibitor | PLpro inhibitor is a potent papain-like protease (PLpro) inhibitor with IC50 of 2.6 μM. |
M9612 | XP-59 | XP-59 is a potent inhibitor of the SARS-CoV Mpro, with a Ki of 0.1 μM. |
M9605 | EIDD-2801 | EIDD-2801 is an orally bioavailable form of a highly potent ribonucleoside analog that inhibits the replication of multiple RNA viruses including SARS-CoV-2, the causative agent of COVID-19. |
M9603 | GS-441524 | GS-441524 is a potent inhibitor of feline infectious peritonitis virus (FIPV) with EC50 of 0.78 μM. |
M9589 | Rifamycin sodium | Rifamycin sodium belongs to the family of ansamycin antibiotics, it is an antibiotic that inhibits bacterial DNA-dependent RNA polymerase. |
M9585 | MAC-545496 | MAC-545496 is potent GraR inhibitor (glycopeptide-resistance-associated protein R), reverses β-lactam resistance in the community-acquired MRSA USA300 strain. |
M9538 | Nisin | Nisin is a bacteriocin produced by a group of Gram-positive bacteria that belongs to Lactococcus and Streptococcus species. |
M9503 | E1210 | E1210 (APX001A) is the first-in-class inhibitor of the fungal protein Gwt1 (GPI-anchored wall transfer protein 1) in the glycosylphosphatidylinositol (GPI) biosynthesis pathway. |
M9501 | AN2718 | AN2718 is a novel boron-containing small molecule that inhibits an essential protein synthesis enzyme, leucyl-transfer RNA synthetase, or LeuRS. |
M9500 | Tavaborole | Tavaborole, also known as AN-2690 is an antifungal agent with activity against Trichophyton species. |
M9462 | Pyronaridine tetraphosphate | Pyronaridine tetraphosphate is a Mannich base anti-malarial with demonstrated efficacy against compound. |
M9461 | Oxyclozanide | Oxyclozanide is a salicylanilide anthelmintic compound, which acts by uncoupling oxidative phosphorylation in flukes. |
M9460 | Tilorone dihydrochloride | Tilorone dihydrochloride is an orally active interferon inducer, used as an antiviral compound. |
M9452 | Sulfaphenazole | Sulfaphenazole is an inhibitor of CYP2C9, which blocks atherogenic and pro-inflammatory effects of linoleic acid mediated by CYP2C9. |
M9441 | GSK656 HCl | GSK656 is a potent Mtb LeuRS inhibitor, shows potent inhibition of Mtb LeuRS (IC50 = 0.20 μM) and in vitro antitubercular activity (Mtb H37Rv MIC = 0.08 μM). |
M9431 | Aureobasidin A | Aureobasidin A (AbA) is a cyclic ester peptide antibiotics which derived from filamentous fungi, and it has strong antifungal ability. |
M9430 | Phleomycin | Phleomycin is a glycopeptide antibiotic. |
M9352 | Gramicidin | Gramicidin is an antimicrobial peptide assembling as channels in membranes and increasing their permeability towards cations. |
M9335 | Cefazolin | Cefazolin is a semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. |
M9334 | Vancomycin | Vancomycin is an antibiotic for the treatment of bacterial infections. |
M9321 | Nourseothricin sulfate | Nourseothricin is a broad-spectrum antibiotic derived from Streptomyces noursei. |
M9305 | Targocil | Targocil is a bacteriostatic inhibitor of wall teichoic acid (WTA) biosynthesis, with MIC90s of 2 μg/ mL for both MRSA and MSSA. |
M9303 | Amenamevir | Amenamevir is a herpes virus helicase-primase inhibitor, with an EC50 of 14 ng/mL against HSVs. |
M9301 | Telithromycin | Telithromycin is a semi-synthetic erythromycin derivative used for mild to moderate respiratory infections. |
M9210 | Ampicillin | Ampicillin is an antibiotic against a variety of gram-positive and gram-negative bacteria. |
M9186 | Bedaquiline | Bedaquiline, a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections. |
M9183 | Baloxavir | Baloxavir is an anti-influenza agent. |
M9170 | Sodium Houttuyfonate | Sodium Houttuyfonate is the active compound of the Houttuynia plant. |
M9169 | Thimerosal | Thimerosal inhibits a wide range of thiol-dependent enzymes and proteins, such as PI3-kinase-dependent methionine synthetase, glutamate transport receptor, and Na++K+ dependence ATPase. |
M9163 | Blasticidin S hydrochloride | Blasticidin S HCl is a potent inhibitor of protein synthesis in both prokaryotic and eukaryotic cells. Blasticidin S hydrochloride is a nucleoside antibiotic isolated from Streptomyces griseochromogenes. |
M9126 | Ac-CoA Synthase Inhibitor 1 | Ac-CoA Synthase Inhibitor 1 (also known as ACSS2 Inhibitor), an anti-virus agent, is a Ac-CoA Synthase Inhibitor. |
M9123 | MBX-4132 | MBX-4132 is a member of a chemical class called oxadiazoles that inhibit trans translation by binding to the bacterial ribosome. |
M9119 | JNJ-632 | JNJ-632 is a potent HVV capsid assembly modulator and HBV replication inhibitor with EC50 of 100-200 nM for genotypes A-D. |
M9112 | AB-423 | AB-423 is an inhibitor of HBV capsid assembly, and potent inhibits HBV replication with EC50/EC90 of 0.08-0.27 μM/0.33-1.32 μM in cells. |
M9110 | Alanosine | Alanosine, also known as L-alanosine, is an amino acid analogue and antibiotic derived from the bacterium Streptomyces alanosinicus with antimetabolite and potential antineoplastic activities. |
M9106 | ST-193 | ST-193 is a potent broad-spectrum arenavirus inhibitor; inhibits Guanarito, Junin, Lassa and Machupo virus with IC50 values of 0.44, 0.62, 1.4 and 3.1 nM, respectively. |
M9030 | Cefquinome sulfate | Cefquinome sulfate is a broad-spectrum fourth-generation cephalosporin antibiotic. |
M9029 | Cefathiamidine | Cefathiamidine is the first generation of cephalosporin antibacterial used for the treatment of respiratory, liver, five senses, urinary tract infections, endocarditis and sepsis. |
M9028 | Nifuratel | Nifuratel is a local antiprotozoal and antifungal agent used in gynecology. |
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