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Abmole Inhibitor Catalog 2017

Anti-infection Anti-infection

Inhibitors

Cat.No.  Name Information
M9847 N-(Ketocaproyl)-D,L-homoserine lactone N-(Ketocaproyl)-D,L-homoserine lactone is a natural, active ligand of LuxR. N-(Ketocaproyl)-D,L-homoserine lactone is also a quorum sensing (QS) autoinducer.
M9845 PBP10 TFA salt PBP10 is a 10-AA peptide with rhodamine conjugated at its N terminus, exerts bactericidal activity against gram-positive and gram-negative bacteria and limits microbial-induced inflammatory effects.
M9843 Triclocarban Triclocarban is an antimicrobial agent.
M9829 NGI-1 NGI-1 (ML414) is an inhibitor of Asparagine (N)-linked glycoslysation, which inhibits the oligosaccharyltransferase, preventing the attachment to the protein.
M9795 8-Epidiosbulbin E acetate 8-Epidiosbulbin E acetate is abundant in Dioscorea bulbifera L. , it exhibits broad-spectrum plasmid-curing activity against multidrug-resistant (MDR) bacteria.
M9775 Fluralaner Fluralaner inhibits γ-aminobutyric acid (GABA)-gated chloride channels (GABACls) and l-glutamate-gated chloride channels (GluCls).
M9772 CHIR-090 CHIR-090 is a very potent and selective LpxC inhibitor, it is also a two-step slow, tight-binding inhibitor of E. coli LpxC with Ki = 4.0 nM.
M9756 Pocapavir Pocapavir (also known as SCH-48973 and V-073) is a potent, selective anti-enterovirus agent.
M9728 Fluensulfone Fluensulfone is a new nematicide for chemical control of plant parasitic nematodes.
M9721 Qstatin Qstatin is a selective inhibitor of quorum sensing (QS) in vibrio species.
M9694 Chlorhexidine Chlorhexidine is a disinfectant and topical anti-infective agent.
M9641 PLpro inhibitor PLpro inhibitor is a potent papain-like protease (PLpro) inhibitor with IC50 of 2.6 μM.
M9612 XP-59 XP-59 is a potent inhibitor of the SARS-CoV Mpro, with a Ki of 0.1 μM.
M9605 EIDD-2801 EIDD-2801 is an orally bioavailable form of a highly potent ribonucleoside analog that inhibits the replication of multiple RNA viruses including SARS-CoV-2, the causative agent of COVID-19.
M9603 GS-441524 GS-441524 is a potent inhibitor of feline infectious peritonitis virus (FIPV) with EC50 of 0.78 μM.
M9589 Rifamycin sodium Rifamycin sodium belongs to the family of ansamycin antibiotics, it is an antibiotic that inhibits bacterial DNA-dependent RNA polymerase.
M9585 MAC-545496 MAC-545496 is potent GraR inhibitor (glycopeptide-resistance-associated protein R), reverses β-lactam resistance in the community-acquired MRSA USA300 strain.
M9538 Nisin Nisin is a bacteriocin produced by a group of Gram-positive bacteria that belongs to Lactococcus and Streptococcus species.
M9503 E1210 E1210 (APX001A) is the first-in-class inhibitor of the fungal protein Gwt1 (GPI-anchored wall transfer protein 1) in the glycosylphosphatidylinositol (GPI) biosynthesis pathway.
M9501 AN2718 AN2718 is a novel boron-containing small molecule that inhibits an essential protein synthesis enzyme, leucyl-transfer RNA synthetase, or LeuRS.
M9500 Tavaborole Tavaborole, also known as AN-2690 is an antifungal agent with activity against Trichophyton species.
M9462 Pyronaridine tetraphosphate Pyronaridine tetraphosphate is a Mannich base anti-malarial with demonstrated efficacy against compound.
M9461 Oxyclozanide Oxyclozanide is a salicylanilide anthelmintic compound, which acts by uncoupling oxidative phosphorylation in flukes.
M9460 Tilorone dihydrochloride Tilorone dihydrochloride is an orally active interferon inducer, used as an antiviral compound.
M9452 Sulfaphenazole Sulfaphenazole is an inhibitor of CYP2C9, which blocks atherogenic and pro-inflammatory effects of linoleic acid mediated by CYP2C9.
M9441 GSK656 HCl GSK656 is a potent Mtb LeuRS inhibitor, shows potent inhibition of Mtb LeuRS (IC50 = 0.20 μM) and in vitro antitubercular activity (Mtb H37Rv MIC = 0.08 μM).
M9431 Aureobasidin A Aureobasidin A (AbA) is a cyclic ester peptide antibiotics which derived from filamentous fungi, and it has strong antifungal ability.
M9430 Phleomycin Phleomycin is a glycopeptide antibiotic.
M9352 Gramicidin Gramicidin is an antimicrobial peptide assembling as channels in membranes and increasing their permeability towards cations.
M9335 Cefazolin Cefazolin is a semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis.
M9334 Vancomycin Vancomycin is an antibiotic for the treatment of bacterial infections.
M9321 Nourseothricin sulfate Nourseothricin is a broad-spectrum antibiotic derived from Streptomyces noursei.
M9305 Targocil Targocil is a bacteriostatic inhibitor of wall teichoic acid (WTA) biosynthesis, with MIC90s of 2 μg/ mL for both MRSA and MSSA.
M9303 Amenamevir Amenamevir is a herpes virus helicase-primase inhibitor, with an EC50 of 14 ng/mL against HSVs.
M9301 Telithromycin Telithromycin is a semi-synthetic erythromycin derivative used for mild to moderate respiratory infections.
M9210 Ampicillin Ampicillin is an antibiotic against a variety of gram-positive and gram-negative bacteria.
M9186 Bedaquiline Bedaquiline, a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections.
M9183 Baloxavir Baloxavir is an anti-influenza agent.
M9170 Sodium Houttuyfonate Sodium Houttuyfonate is the active compound of the Houttuynia plant.
M9169 Thimerosal Thimerosal inhibits a wide range of thiol-dependent enzymes and proteins, such as PI3-kinase-dependent methionine synthetase, glutamate transport receptor, and Na++K+ dependence ATPase.
M9163 Blasticidin S hydrochloride Blasticidin S HCl is a potent inhibitor of protein synthesis in both prokaryotic and eukaryotic cells. Blasticidin S hydrochloride is a nucleoside antibiotic isolated from Streptomyces griseochromogenes.
M9126 Ac-CoA Synthase Inhibitor 1 Ac-CoA Synthase Inhibitor 1 (also known as ACSS2 Inhibitor), an anti-virus agent, is a Ac-CoA Synthase Inhibitor.
M9123 MBX-4132 MBX-4132 is a member of a chemical class called oxadiazoles that inhibit trans translation by binding to the bacterial ribosome.
M9119 JNJ-632 JNJ-632 is a potent HVV capsid assembly modulator and HBV replication inhibitor with EC50 of 100-200 nM for genotypes A-D.
M9112 AB-423 AB-423 is an inhibitor of HBV capsid assembly, and potent inhibits HBV replication with EC50/EC90 of 0.08-0.27 μM/0.33-1.32 μM in cells.
M9110 Alanosine Alanosine, also known as L-alanosine, is an amino acid analogue and antibiotic derived from the bacterium Streptomyces alanosinicus with antimetabolite and potential antineoplastic activities.
M9106 ST-193 ST-193 is a potent broad-spectrum arenavirus inhibitor; inhibits Guanarito, Junin, Lassa and Machupo virus with IC50 values of 0.44, 0.62, 1.4 and 3.1 nM, respectively.
M9030 Cefquinome sulfate Cefquinome sulfate is a broad-spectrum fourth-generation cephalosporin antibiotic.
M9029 Cefathiamidine Cefathiamidine is the first generation of cephalosporin antibacterial used for the treatment of respiratory, liver, five senses, urinary tract infections, endocarditis and sepsis.
M9028 Nifuratel Nifuratel is a local antiprotozoal and antifungal agent used in gynecology.


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