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Inhibitors
| Cat.No. | Name | Information |
|---|---|---|
| M10473 | MK-3118 | MK-3118 is a novel glucan synthase inhibitor with activity against many echinocandin-resistant strains of Candida due to differential avidity for the target site compared to echinocandins. |
| M10444 | Oteseconazole | Oteseconazole (VT-1161) is an orally active anti-fungal agent, potently binds to and inhibits Candida albicans CYP51 (Kd <39 nM). |
| M10421 | Sodium citrate (dihydrate) | Sodium citrate dehydrate is an anticoagulant and also used as a buffer and food preservatives. |
| M10360 | Arteannuin B | Arteannuin B co-occurs with artemisinin, Arteannuin B shows anti-SARS-CoV-2 potential with an EC50 of 10.28 μM. |
| M10359 | Dihydroartemisinic acid | Dihydroartemisinic acid is a natural product from Artemisia annua and the main direct precursor of artemisinin, which is a medicinal herb that is widely used to treat Malaria. |
| M10339 | Fexinidazole | Fexinidazole (also known as Hoe-239) is an orally active, potent antiparasitic agent. |
| M10241 | Polymyxin B nonapeptide TFA | Polymyxin B nonapeptide TFA is a cyclic peptide from the naturally occurring peptide polymyxin B, it can increase the permeability of the outer membrane of Gram-negative bacteria toward hydrophobic antibiotics. |
| M10232 | Cefotaxime | Cefotaxime is an inhibitor of penicillin binding protein. |
| M10178 | Cefoperazone sodium | Cefoperazone sodium is a semi-synthetic, broad-spectrum, beta-lactamase resistant antibiotic with bactericidal activity. |
| M10163 | Baloxavir marboxil | Baloxavir marboxil is a novel cap-dependent endonuclease inhibitor for the treatment of influenza A and B virus infections. |
| M10148 | Juglone | Juglone is a natural naphthoquinone found in the black walnut (Juglans regia) shows antimicrobial activity. |
| M10127 | Azathramycin | Azathramycin is an antibiotic, binding to the 50S subunit of the bacterial ribosome, and thus inhibits translation of mRNA. |
| M10084 | AMY-101 acetate | AMY-101 acetate is a peptidic inhibitor of the central complement component C3 (KD = 0.5 nM). |
| M10082 | Amodiaquine | Amodiaquine is a 4-aminoquinoline compound related to chloroquine, used as an antimalarial and anti-inflammatory agent. |
| M10031 | Lysozyme (from egg white) | Lysozyme (from egg white) is a bactericidal enzyme present in chicken eggs, and it lyses gram-positive bacteria. |
| M10028 | Phe-Arg-β-naphthylamide 2HCl | Phe-Arg-β-naphthylamide 2HCl is an efflux pump inhibitor (EPI), it acts on the major multidrug resistance efflux transporters of Gram-negative bacteria. |
| M9963 | Allicin | Allicin has highly potent antimicrobial activity, and inhibits growth of a variety of microorganisms, among them antibiotic-resistant strains. |
| M9955 | LL-37 (Human) | Antibacterial Protein LL-37 (human) is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity. |
| M9847 | N-(Ketocaproyl)-D,L-homoserine lactone | N-(Ketocaproyl)-D,L-homoserine lactone is a natural, active ligand of LuxR. N-(Ketocaproyl)-D,L-homoserine lactone is also a quorum sensing (QS) autoinducer. |
| M9845 | PBP10 TFA salt | PBP10 is a 10-AA peptide with rhodamine conjugated at its N terminus, exerts bactericidal activity against gram-positive and gram-negative bacteria and limits microbial-induced inflammatory effects. |
| M9843 | Triclocarban | Triclocarban is an antimicrobial agent. |
| M9829 | NGI-1 | NGI-1 (ML414) is an inhibitor of Asparagine (N)-linked glycoslysation, which inhibits the oligosaccharyltransferase, preventing the attachment to the protein. |
| M9795 | 8-Epidiosbulbin E acetate | 8-Epidiosbulbin E acetate is abundant in Dioscorea bulbifera L. , it exhibits broad-spectrum plasmid-curing activity against multidrug-resistant (MDR) bacteria. |
| M9775 | Fluralaner | Fluralaner inhibits γ-aminobutyric acid (GABA)-gated chloride channels (GABACls) and l-glutamate-gated chloride channels (GluCls). |
| M9772 | CHIR-090 | CHIR-090 is a very potent and selective LpxC inhibitor, it is also a two-step slow, tight-binding inhibitor of E. coli LpxC with Ki = 4.0 nM. |
| M9756 | Pocapavir | Pocapavir (also known as SCH-48973 and V-073) is a potent, selective anti-enterovirus agent. |
| M9728 | Fluensulfone | Fluensulfone is a new nematicide for chemical control of plant parasitic nematodes. |
| M9721 | Qstatin | Qstatin is a selective inhibitor of quorum sensing (QS) in vibrio species. |
| M9694 | Chlorhexidine | Chlorhexidine is a disinfectant and topical anti-infective agent. |
| M9641 | PLpro inhibitor | PLpro inhibitor is a potent papain-like protease (PLpro) inhibitor with IC50 of 2.6 μM. |
| M9612 | XP-59 | XP-59 is a potent inhibitor of the SARS-CoV Mpro, with a Ki of 0.1 μM. |
| M9605 | Molnupiravir (EIDD-2801) | Molnupiravir (EIDD-2801) is an orally bioavailable form of a highly potent ribonucleoside analog that inhibits the replication of multiple RNA viruses including SARS-CoV-2, the causative agent of COVID-19. |
| M9603 | GS-441524 | GS-441524 is a potent inhibitor of feline infectious peritonitis virus (FIPV) with EC50 of 0.78 μM. |
| M9589 | Rifamycin sodium | Rifamycin sodium belongs to the family of ansamycin antibiotics, it is an antibiotic that inhibits bacterial DNA-dependent RNA polymerase. |
| M9585 | MAC-545496 | MAC-545496 is potent GraR inhibitor (glycopeptide-resistance-associated protein R), reverses β-lactam resistance in the community-acquired MRSA USA300 strain. |
| M9538 | Nisin | Nisin is a bacteriocin produced by a group of Gram-positive bacteria that belongs to Lactococcus and Streptococcus species. |
| M9503 | E1210 | E1210 (APX001A) is the first-in-class inhibitor of the fungal protein Gwt1 (GPI-anchored wall transfer protein 1) in the glycosylphosphatidylinositol (GPI) biosynthesis pathway. |
| M9501 | AN2718 | AN2718 is a novel boron-containing small molecule that inhibits an essential protein synthesis enzyme, leucyl-transfer RNA synthetase, or LeuRS. |
| M9500 | Tavaborole | Tavaborole, also known as AN-2690 is an antifungal agent with activity against Trichophyton species. |
| M9462 | Pyronaridine tetraphosphate | Pyronaridine tetraphosphate is a Mannich base anti-malarial with demonstrated efficacy against compound. |
| M9461 | Oxyclozanide | Oxyclozanide is a salicylanilide anthelmintic compound, which acts by uncoupling oxidative phosphorylation in flukes. |
| M9460 | Tilorone dihydrochloride | Tilorone dihydrochloride is an orally active interferon inducer, used as an antiviral compound. |
| M9452 | Sulfaphenazole | Sulfaphenazole is an inhibitor of CYP2C9, which blocks atherogenic and pro-inflammatory effects of linoleic acid mediated by CYP2C9. |
| M9441 | GSK656 HCl | GSK656 is a potent Mtb LeuRS inhibitor, shows potent inhibition of Mtb LeuRS (IC50 = 0.20 μM) and in vitro antitubercular activity (Mtb H37Rv MIC = 0.08 μM). |
| M9431 | Aureobasidin A | Aureobasidin A (AbA) is a cyclic ester peptide antibiotics which derived from filamentous fungi, and it has strong antifungal ability. |
| M9430 | Phleomycin | Phleomycin is a glycopeptide antibiotic. |
| M9352 | Gramicidin | Gramicidin is an antimicrobial peptide assembling as channels in membranes and increasing their permeability towards cations. |
| M9335 | Cefazolin | Cefazolin is a semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. |
| M9334 | Vancomycin | Vancomycin is an antibiotic for the treatment of bacterial infections. |
| M9321 | Nourseothricin sulfate | Nourseothricin is a broad-spectrum antibiotic derived from Streptomyces noursei. |
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