Catalog

AMPK Adenosine Monophosphate Activated Protein Kinase

Inhibitors

Cat.No.	Name	Information
M5336	Phenformin HCl	Phenformin HCl is a hydrochloride salt of phenformin that is an anti-diabetic drug from the biguanide class. It activates AMPK, increasing activity and phosphorylation.
M5326	HTH-01-015	HTH-01-015 is a potent and selective NUAK1 inhibitor with IC50 of 100 nM, >100-fold selectivity over NUAK2.
M5207	ETC-1002	ETC-1002 (ESP-55016) is a novel, first-in-class, orally available, once-daily LDL-C lowering small molecule.
M4897	AICAR	AICAR is an activator of AMP-activated protein kinase (AMPK), down-regulates the insulin receptor expression in HepG2 cells.
M3946	BML-275	BML-275 (Dorsomorphin) is a cell-permeable pyrazolopyrimidine compound shown to be an AMPK inhibitor with Ki of 109 nM in cell-free assays.
M3444	A-769662	A-769662 is a potent, reversible AMPK activator with EC50of 0.8 μM, little effect on GPPase/FBPase activity.
M3132	WZ4003	WZ4003 is a highly specific NUAK kinase inhibitor with IC50 of 20 nM and 100 nM for NUAK1 and NUAK2, respectively, without significant inhibition on 139 other kinases.
M2238	Dorsomorphin dihydrochloride	Dorsomorphin (BML-275) dihydrochloride is a potent and selective AMPK inhibitor with Ki value of 109 nM.