|M9764||MK-3903||MK-3903 is a potent and selective AMPK activator (EC50 = 8 nM).|
|M8095||PF-06409577||PF-06409577 is a potent and selective activator of 5′ adenosine monophosphate-activated protein kinase (AMPK).|
|M5336||Phenformin HCl||Phenformin HCl is a hydrochloride salt of phenformin that is an anti-diabetic drug from the biguanide class. It activates AMPK, increasing activity and phosphorylation.|
|M5326||HTH-01-015||HTH-01-015 is a potent and selective NUAK1 inhibitor with IC50 of 100 nM, >100-fold selectivity over NUAK2.|
|M5207||ETC-1002||ETC-1002 (ESP-55016) is a novel, first-in-class, orally available, once-daily LDL-C lowering small molecule.|
|M4897||AICAR||AICAR is an activator of AMP-activated protein kinase (AMPK), down-regulates the insulin receptor expression in HepG2 cells.|
|M4233||Ginkgolide C||Ginkgolide C is a flavone isolated from Ginkgo biloba leaves, possessing multiple biological functions, such as decreasing platelet aggregation and ameliorating Alzheimer disease.|
|M3946||BML-275||BML-275 (Dorsomorphin) is a cell-permeable pyrazolopyrimidine compound shown to be an AMPK inhibitor with Ki of 109 nM in cell-free assays.|
|M3444||A-769662||A-769662 is a potent, reversible AMPK activator with EC50of 0.8 μM, little effect on GPPase/FBPase activity.|
|M3132||WZ4003||WZ4003 is a highly specific NUAK kinase inhibitor with IC50 of 20 nM and 100 nM for NUAK1 and NUAK2, respectively, without significant inhibition on 139 other kinases.|
|M2902||OTSSP167||OTSSP167 is a highly potent MELK (maternal embryonic leucine zipper kinase) inhibitor with IC50 of 0.41 nM.|
|M2238||Dorsomorphin (Compound C) dihydrochloride||Dorsomorphin (BML-275) dihydrochloride is a potent and selective AMPK inhibitor with Ki value of 109 nM.|
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