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Abmole Inhibitor Catalog 2017

AhR Aryl Hydrocarbon Receptor

Inhibitors

Cat.No.  Name Information
M10486 GNF351 GNF351 is a full aryl hydrocarbon receptor (AHR) antagonist. GNF351 competes with a photoaffinity AHR ligand for binding to the AHR with an IC50 of 62 nM.
M10243 D-Kynurenine D-kynurenine is a metabolite of D-tryptophan, which can be used as a biological precursor of KYNA and 3-hydroxykynurenine.
M9723 L-Kynurenine L-Kynurenine is an aryl hydrocarbon receptor agonist.
M9714 CAY10465 CAY10465 is an analog of resveratrol acting as a potent and selective aryl hydrocarbon receptor agonist, with a Ki of 0.2 nM.
M9693 PDM2 PDM2 is a potent and selective aryl hydrocarbon receptor (AhR) antagonist, with a Ki of 1.2 nM.
M9490 YL-109 YL-109 is a novel anticancer agent, which can inhibit breast cancer cell growth and invasiveness in vitro and in vivo, YL-109 is also an STUB1 enhancer.
M8807 Perillaldehyde Perillaldehyde inhibits BaP-induced AHR activation and ROS production, inhibits BaP/AHR-mediated release of the CCL2 chemokine, and activats the NRF2/HO1 antioxidant pathway.
M7727 CH-223191 CH-223191 is a potent and specific aryl hydrocarbon receptor (AhR) antagonist. *The compound is unstable in solutions, freshly prepared is recommended
M4783 Diosimin Diosimin is a flavonoid glycoside found in citrus fruits, hyssop, and rosemary.
M2577 StemRegenin 1 StemRegenin 1 is an AhR inhibitor with IC50 of 127 nM.


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