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StemRegenin 1

Cat. No. M2577
StemRegenin 1 Structure
Synonym:

SR1

Size Price Availability Quantity
25mg USD 100 In stock
50mg USD 180 In stock
100mg USD 310 In stock
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Quality Control
Biological Activity

StemRegenin 1 is an AhR inhibitor with IC50 of 127 nM.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 429.54
Formula C24H23N5OS
CAS Number 1227633-49-9
Purity >99%
Solubility DMSO 70 mg/mL
Storage at -20°C
  Catalog
Abmole Inhibitor Catalog 2017




Keywords: StemRegenin 1, SR1 supplier, AhR, inhibitors

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