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YH439

Cat. No. M8862
YH439 Structure
Synonym:

YH439

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Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

YH439 is an aryl hydrocarbon receptor activator

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 330.45
Formula C12H14N2O3S3
CAS Number 130112-42-4
Purity >98%
Solubility DMSO: ≥5 mg/mL
Storage at -20°C
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  Catalog
Abmole Inhibitor Catalog 2017




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