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Inhibitors
| Cat.No. | Name | Information |
|---|---|---|
| M21332 | Calmidazolium chloride | Calmidazolium chloride (R 24571) is a calmodulin antagonist that antagonizes CaM-dependent phosphodiesterase and calmodulin-induced activation of Ca2+-transporting ATPase in erythrocytes with IC50s of 0.15 and 0.35 μM, respectively. it is also used in anticancer studies. It binds CaMK with a Kd value of 3 nM. |
| M14559 | Syntide 2 TFA | Syntide 2 (TFA), a Ca2+- and calmodulin (CaM)-dependent protein kinase II (CaMKII) substrate peptide, selectively inhibits the gibberellin (GA) response, leaving constitutive and abscisic acid-regulated events unaffected. |
| M14558 | KN-93 phosphate | KN-93 phosphate is a novel membrane-permeant synthetic inhibitor of purified neuronal CaMK-II, with Ki of 370 nM. |
| M14557 | CaMKII-IN-1 | CaMKII-IN-1 is a potent and highly selective CaMKII inhibitor with IC50 of 63 nM; significantly high selectivity against CaMKIV, MLCK, p38a, Akt1, and PKC. |
| M14556 | Autocamtide-2-related inhibitory peptide TFA | Autocamtide-2-related inhibitory peptide (TFA) is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM. |
| M9624 | KN-93 hydrochloride | KN-93 hydrochloride is a cell-permeable inhibitor of Ca2+/calmodulin-dependent protein kinase II (CaMK-II) with a Ki of 370 nM. |
| M9266 | STO-609 acetate | STO-609 acetate is a cell-permeable inhibitor of calcium/calmodulin-dependent kinase kinases (CaMKK) isoforms CaMKKα and CaMKKβ with Ki of 80 and 15 ng/ml, respectively. |
| M9254 | KN-92 phosphate | KN-92 is an inactive analog of the CaM kinase II inhibitor KN-93. |
| M7481 | W-7 hydrochloride | W-7 Hydrochloride is a selective calmodulin antagonist. W-7 Hydrochloride inhibits Ca2+ -calmodulin-dependent phosphodiesterase and Myosin light chain kinase. The IC50 values were 28 μM and 51 μM, respectively. W-7 Hydrochloride can induce apoptosis and has anti-cancer activity. |
| M6868 | KN 93 | KN 93 is a caM kinase II inhibitor; also K + channel blocker (K V). |
| M3866 | KN-92 | KN-92 is an inactive analog of the CaM kinase II inhibitor KN-93. |
| M3623 | A23187 | A23187 is a calcium ionophore that induces Ca2+-dependent cell death by increasing intracellular calcium concentration. |
| M1928 | KN-62 | KN-62 is a selective, cell permeable inhibitor of calcium/calmodulin-dependent kinase II (CaMKII; IC50 = 900 nM). |
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