About 11 results found for searched term "AZ20" (0.058 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1696 | Cediranib | VEGFR/PDGFR |
| AZD2171; NSC-732208 | ||
| Cediranib (AZD2171) inhibited VEGFR2 and KDR phosphorylation with IC50s of 0.4 and 0.5 nM, respectively. | ||
| M2299 | AZD2014 | mTOR |
| Vistusertib | ||
| AZD2014 is a novel dual mTORC1 and mTORC2 inhibitor with potential antineoplastic activity. | ||
| M2412 | AZ20 | ATM/ATR |
| AZ20 is a novel potent and selective inhibitor of ATR kinase with IC50 of 5 nM, 8-fold selectivity over mTOR. | ||
| M45342 | AZD-2207 | Cannabinoid |
| AZD-2207 is a cannabinoid receptor CB1 antagonist and highly lipophilic compound that can be used in studies related to type 2 diabetic disease and obesity. | ||
| M4810 | AZD-1208 | Pim |
| AZD1208 | ||
| AZD1208 is a potent, highly selective, and orally available Pim kinase inhibitor that effectively inhibits all three isoforms at <5 nM or <150 nM in enzyme and cell assays, respectively. | ||
| M6294 | AZD-7594 | GCR |
| AZ13189620 | ||
| AZD7594 is an inhaled, nonsteroidal, potent, and selective modulator of the glucocorticoid receptor (GR). It is being developed for once-daily treatment of chronic obstructive pulmonary disease and asthma, either alone or in combination with a bronchodilator. | ||
| M6475 | AZ 10606120 dihydrochloride | P2 Receptor |
| AZ 10606120 dihydrochloride is a potent P2X 7 receptor antagonist. | ||
| M6481 | AZD 2066 | Others |
| AZD 2066 is a mGlu 5 antagonist; orally bioavailable and brain penetrant. | ||
| M10377 | Golidocitinib (AZD4205) | JAK |
| AZD-4205; Golidocitinib | ||
| Golidocitinib (AZD4205) is a novel potent and selective janus kinase 1 (JAK1) inhibitor, with IC50 value of 73 nM. | ||
| M13921 | AZD2098 | CCR |
| AZD2098 is a potent and selective CC-chemokine receptor 4 (CCR4) inhibitor with pIC50s of 7.8, 8.0, 8.0 and 7.6 for human, rat, mouse and dog respectively, used for asthma research. | ||
| M28240 | AZD4320 | Bcl-2 |
| AZD4320 is a novel BH3-mimicking dual BCL2/BCLxL inhibitor with IC50s of 26 nM, 17 nM, and 170 nM for KPUM-MS3, KPUM-UH1, and STR-428 cells, respectively. | ||
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