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 About 19 results found for searched term "AZ20" (0.031 seconds)

Cat.No.  Name Information
M1696 Cediranib Cediranib (AZD2171) inhibited VEGFR2 and KDR phosphorylation with IC50s of 0.4 and 0.5 nM, respectively.
M1810 AZD5438 AZD5438 is a novel, orally bioavailable inhibitor of cyclin-dependent kinase (CDK) 1, 2 and 9 (IC50 values are 16, 6 and 20 nM respectively).
M1856 Thiazovivin Thiazovivin is a selective small molecule Rho-associated kinase (ROCK) inhibitor which significantly improves (200-fold) the efficiency of iPSC generation from human fibroblasts.
M2299 AZD2014 AZD2014 is a novel dual mTORC1 and mTORC2 inhibitor with potential antineoplastic activity.
M2412 AZ20 AZ20 is a novel potent and selective inhibitor of ATR kinase with IC50 of 5 nM, 8-fold selectivity over mTOR.
M3456 Chlorpromazine hydrochloride Chlorpromazine hydrochloride is an antagonist of D2, 5HT2A, potassium and sodium channels. The Ki of Chlorpromazine Hydrochloride to D2 and 5HT2A were 363 nM and 8.3 nM, respectively. Chlorpromazine also excites the 20S proteasome. *The compound is unstable in solutions, freshly prepared is recommended
M4810 AZD-1208 AZD1208 is a potent, highly selective, and orally available Pim kinase inhibitor that effectively inhibits all three isoforms at <5 nM or <150 nM in enzyme and cell assays, respectively.
M5297 Q203 Q203 (IAP6) is a midazopyridine amide compound. Q203 is active against Mycobacterium tuberculosis H37Rv with an MIC50 of 2.7 nM in culture broth medium. IC50 & Target: MIC50: 2.7 nM (Mycobacterium tuberculosis H37Rv).
M5501 Ceftazidime Ceftazidime(GR20263) is an antibiotic useful for the treatment of a number of bacterial infections.
M6294 AZD-7594 AZD7594 is an inhaled, nonsteroidal, potent, and selective modulator of the glucocorticoid receptor (GR). It is being developed for once-daily treatment of chronic obstructive pulmonary disease and asthma, either alone or in combination with a bronchodilator.
M6389 1-Aminobenzotriazole (ABT) 1-Aminobenzotriazole (ABT) is a cytochrome P450 inhibitor; inhibits 20-HETE synthesis.
M6475 AZ 10606120 dihydrochloride AZ 10606120 dihydrochloride is a potent P2X 7 receptor antagonist.
M6481 AZD 2066 AZD 2066 is a mGlu 5 antagonist; orally bioavailable and brain penetrant.
M8773 Liarozole dihydrochloride Liarozole (R 75251, R75,251) is an orally active benzimidazole-based retinoic acid (RA) metabolism blocking agent (RAMBA) that targets multiple P450 enzymes, including aromatase (CYP19), 17-hydroxylase/17,20-lyase (CYP17A1), 11-hydroxylase (CYP11B1), and RA 4-hydroxylase (CYP26).
M10377 Golidocitinib (AZD4205) Golidocitinib (AZD4205) is a novel potent and selective janus kinase 1 (JAK1) inhibitor, with IC50 value of 73 nM.
M10676 Tegoprazan Tegoprazan (CJ-12420, IN-A001, K-CAB, LXI-15028) is a potassium-competitive acid blocker and a potent, oral active and highly selective inhibitor of gastric H+/K+-ATPase that could control gastric acid secretion and motility, with IC50 values ranging from 0.29-0.52 μM for porcine, canine, and human H+/K+-ATPases in vitro.
M10834 Indeglitazar Indeglitazar (PPM 204) is an orally active PPAR pan-agonist that acts on PPARα, PPARδ and PPARγ.
M13921 AZD2098 AZD2098 is a potent and selective CC-chemokine receptor 4 (CCR4) inhibitor with pIC50s of 7.8, 8.0, 8.0 and 7.6 for human, rat, mouse and dog respectively, used for asthma research.
M14938 YAP/TAZ inhibitor-1 YAP/TAZ inhibitor-1 is a YAP/TAZ inhibitor extracted from patent WO2017058716A1, Compound 1, has an IC50 of <0.100 μΜ in firefly luciferase assay.

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