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Salvianolic acid B is a cell protective antioxidant and free radical scavenger being investigated for a variety of conditions from ischemic heart disorders to Alzheimer′s disease. Several mechanisms of action have been proposed including EGFR, PDGF and MMP-9 inhibition and inhibition of the TGF-β1/Smads and NF-κB signaling pathways. Salvianolic acid B acts as scavengers of reactive oxygen species, reduces the adherence of leukocytes to endothelial cells, inhibits matrix metalloproteinases and inflammation. It has cardioprotective effects as it reduces lipid peroxidation in damaged cardiac tissue and decreases the leakage of lactic acid dehydrogenase.
*The compound is unstable in solutions, freshly prepared is recommended.
| Molecular Weight | 718.62 |
| Formula | C36H30O16 |
| CAS Number | 115939-25-8 |
| Solubility (25°C) | DMSO 20 mg/mL Water 25 mg/mL (ultrasonic and adjust pH to 3 with HCl) |
| Storage | Powder -20°C 3 years ; 4°C 2 years |
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