Free shipping on all orders over $ 500

Plantamajoside

Cat. No. M4720
Plantamajoside Structure
Size Price Availability Quantity
20mg USD 280 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

Plantamajoside is a hydroxycinnamic acid, which used as a biomarker in chemotaxonomical studies.

Customer Product Validations & Biological Datas
Source BMC Complement Altern Med (2017). Figure 2. Plantamajoside
Method Western blotting
Cell Lines HUVECs
Concentrations 10 μM
Incubation Time 24 h
Results In contrast, the co-treatment with 10 μM PM and 100 μg/mLof glycer-AGEs reduced protein expression
Source BMC Complement Altern Med (2017). Figure 1. Plantamajoside
Method MTT assay
Cell Lines HUVECs
Concentrations 10 μM
Incubation Time 24 h
Results We checked the PM cytotoxicity at 100 μM PM for 24 h and then treated with the PM only up to 10 μM PM after all experiments; NAC was not cytotoxic up to 1 mM for 24 h
Protocol
Cell Experiment
Cell lines MDA-MB-231 cells and 4T1 cells
Preparation method Cell viability assay was also performed on CHO cells to investigate the side effect of PMS on normal cells. The PMS concentration closed to IC50 (data not shown) for MDA-MB-231 cells and 4T1 cells at 36 h time point was chosen to treat CHO.
Concentrations 100 μg/mL
Incubation time 36 h
Animal Experiment
Animal models BALB/c mice
Formulation
Dosages 200 mg/kg
Administration oral
Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 640.59
Formula C29H36O16
CAS Number 104777-68-6
Purity >98%
Solubility DMSO: ≥ 30 mg/mL
Storage at -20°C
References

Plantamajoside, a potential anti-tumor herbal medicine inhibits breast cancer growth and pulmonary metastasis by decreasing the activity of matrix metalloproteinase-9 and -2.
Pei S, et al. BMC Cancer. 2015 Dec 16;15:965. PMID: 26674531.

Related Others Products
Brassinolide

Brassinolide is a plant steroid that promotes cell elongation and cell devision and thus regulates plant growth and development.

Hastatoside

Hastatoside is isolated from Verbena species and exhibits various biological activities including sleep-promoting.

Ademetionine

Ademetionine(S-adenosyl-l-methionine; SAMe) is a naturally-occurring substance which is a major source of methyl groups in the brain.

6-Aminocaproic acid

6-Aminocaproic acid is a derivative and analogue of the amino acid lysine.

8-Prenylnaringenin

8-Prenylnaringenin

  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Plantamajoside supplier, Others, inhibitors

Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2017 AbMole BioScience. All Rights Reserved.