Plantamajoside is a hydroxycinnamic acid, which used as a biomarker in chemotaxonomical studies.
|Source||BMC Complement Altern Med (2017). Figure 2. Plantamajoside|
|Incubation Time||24 h|
|Results||In contrast, the co-treatment with 10 μM PM and 100 μg/mLof glycer-AGEs reduced protein expression|
|Source||BMC Complement Altern Med (2017). Figure 1. Plantamajoside|
|Incubation Time||24 h|
|Results||We checked the PM cytotoxicity at 100 μM PM for 24 h and then treated with the PM only up to 10 μM PM after all experiments; NAC was not cytotoxic up to 1 mM for 24 h|
|Cell lines||MDA-MB-231 cells and 4T1 cells|
|Preparation method||Cell viability assay was also performed on CHO cells to investigate the side effect of PMS on normal cells. The PMS concentration closed to IC50 (data not shown) for MDA-MB-231 cells and 4T1 cells at 36 h time point was chosen to treat CHO.|
|Incubation time||36 h|
|Animal models||BALB/c mice|
|Body Surface Area (m2)||0.007||0.025||0.15||0.05||0.02||0.5|
|Animal A (mg/kg) = Animal B (mg/kg) multiplied by||Animal B Km|
|Animal A Km|
For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.
|Solubility||DMSO: ≥ 30 mg/mL|
Plantamajoside, a potential anti-tumor herbal medicine inhibits breast cancer growth and pulmonary metastasis by decreasing the activity of matrix metalloproteinase-9 and -2.
Pei S, et al. BMC Cancer. 2015 Dec 16;15:965. PMID: 26674531.
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