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Jasminoside B

Cat. No. M40047
Jasminoside B Structure
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Biological Activity

Jasminoside B is a natural compound with immunosuppressive activity.

Chemical Information
Molecular Weight 346.37
Formula C16H26O8
CAS Number 214125-04-9
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Jie Yang et al. Food Sci Nutr. Multiple responses optimization of antioxidative components extracted from Fenugreek seeds using response surface methodology to identify their chemical compositions

[2] Jing Xu et al. J Anal Methods Chem. Quality Evaluation of Decoction Pieces of Gardeniae Fructus Based on Qualitative Analysis of the HPLC Fingerprint and Triple-Q-TOF-MS/MS Combined with Quantitative Analysis of 12 Representative Components

[3] Wei Zhou et al. J Chromatogr A. A two-step ultra-high-performance liquid chromatography-quadrupole/time of flight mass spectrometry with mass defect filtering method for rapid identification of analogues from known components of different chemical structure types in Fructus Gardeniae-Fructus Forsythiae herb pair extract and in rat's blood

[4] Y C Shen et al. Planta Med. New secoiridoid glucosides from Jasminum lanceolarium

[5] T Tanahashi et al. Planta Med. Jasamplexosides A, B and C: Novel Dimeric and Trimeric Secoiridoid Glucosides from Jasminum amplexicaule

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