Free shipping on all orders over $ 500


Cat. No. M5648
Floxuridine Structure

Deoxyfluorouridine, FDUR, NSC 27640

Size Price Availability Quantity
100mg USD 120 In stock
500mg USD 300 In stock
Bulk Inquiry?

Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Floxuridine is an antineoplastic antimetabolite, used in the treatment of colon carcinoma and colorectal cancer that has metastasized to the liver.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 246.19
Formula C9H11FN2O5
CAS Number 50-91-9
Purity >99%
Solubility 49 mg/mL in DMSO
Storage at -20°C

Synthesis and in vitro evaluation of bile acid prodrugs of floxuridine to target the liver.
Vivian D, et al. Int J Pharm. 2014 Nov 20;475(1-2):597-604. PMID: 25219859.

Related DNA/RNA Synthesis Products

Favipiravir (T-705) is a potent and selective RNA-dependent RNA polymerase inhibitor, used to treat influenza virus infections.


Vidarabine is an antiviral drug by interfering with the synthesis of viral DNA, used to treat herpes simplex and varicella zoster viruses.


Uridine is a nucleoside, contains a uracil attached to a ribose ring via a β-N1-glycosidic bond.


Rifampin is a DNA-dependent RNA polymerase inhibitor, used to treat a number of bacterial infections.

Mitomycin C

Mitomycin C is an antineoplastic antibiotic by inhibiting DNA synthesis, used to treat different cancers.

Abmole Inhibitor Catalog 2017

Keywords: Floxuridine, Deoxyfluorouridine, FDUR, NSC 27640 supplier, DNA/RNA Synthesis, inhibitors

Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2017 AbMole BioScience. All Rights Reserved.