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Eleutheroside B1

Cat. No. M18584
Eleutheroside B1 Structure
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Biological Activity

Eleutheroside B1

Chemical Information
CAS Number 16845-16-2
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Xinyu Yang, et al. Ultrason Sonochem. Tea saponin additive to extract eleutheroside B and E from Eleutherococcus senticosus by ultrasonic mediation and its application in a semi-pilot scale

[2] Li-Hao Xiao, et al. Zhongguo Zhong Yao Za Zhi. [Research on chemical constituents from Artemisia annua Ⅰ]

[3] Wen Yan, et al. Int J Mol Med. Effect of eleutheroside B1 on non‑coding RNAs and protein profiles of influenza A virus‑infected A549 cells

[4] Wen Yan, et al. Int J Mol Med. Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation

[5] Haifeng Wu, et al. Molecules. Benzyl 2-β-glucopyranosyloxybenzoate, a new phenolic acid glycoside from Sarcandra glabra

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