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D-(+)-Cellotriose

Cat. No. M39984
D-(+)-Cellotriose Structure
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Biological Activity

D-(+)-Cellotriose (Cellotriose) is an oligosaccharide, it is an intermediate in the enzyme hydrolysis of cellulose.

Chemical Information
Molecular Weight 504.44
Formula C18H32O16
CAS Number 33404-34-1
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Frédéric Kerff et al. Microbiol Spectr. Common scab disease: structural basis of elicitor recognition in pathogenic Streptomyces species

[2] Zorica Ubiparip et al. Appl Microbiol Biotechnol. Engineering of cellobiose phosphorylase for the defined synthesis of cellotriose

[3] Joy M Johnson et al. Plant Physiol. A Poly(A) Ribonuclease Controls the Cellotriose-Based Interaction between Piriformospora indica and Its Host Arabidopsis

[4] Li-Chu Tsai et al. J Mol Biol. Crystal structure of truncated Fibrobacter succinogenes 1,3-1,4-beta-D-glucanase in complex with beta-1,3-1,4-cellotriose

[5] H Hatakeyama et al. Carbohydr Res. Studies on the isothermal crystallization of D-glucose and cellulose oligosaccharides by differential scanning calorimetry

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