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Inhibitors
| Cat.No. | Name | Information |
|---|---|---|
| M3719 | K145 hydrochloride | K145 hydrochloride is a selective SphK2 inhibitor with an IC50 of 4.30±0.06 μM , while no inhibition of SphK1 at concentrations up to 10 μM. |
| M2930 | PF-543 | PF-543, a novel sphingosine-competitive inhibitor of SphK1, inhibits SphK1 with IC50 and Ki of 2.0 nM and 3.6 nM, exhibits >100-fold selectivity over the SphK2 isoform. |
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