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  Catalog
Abmole Inhibitor Catalog 2017

SPHK Sphingosine kinase

Inhibitors

Cat.No.  Name Information
M3719 K145 hydrochloride K145 hydrochloride is a selective SphK2 inhibitor with an IC50 of 4.30±0.06 μM , while no inhibition of SphK1 at concentrations up to 10 μM.
M2930 PF-543 PF-543, a novel sphingosine-competitive inhibitor of SphK1, inhibits SphK1 with IC50 and Ki of 2.0 nM and 3.6 nM, exhibits >100-fold selectivity over the SphK2 isoform.


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