S6 Kinase S6 Kinase

Inhibitors

Cat.No.	Name	Information
M20745	S6K-18	S6K-18 is a highly selective inhibitor of ribosomal protein S6 kinase beta-1 (S6K1, p70S6K, p70-S6K).
M14184	LJH685	LJH685 is a potent, ATP-competitive and selective RSK inhibitor, inhibits RSK1, 2, and 3 biochemical activities with IC50s of 6, 5, 4 nM, respectively.
M14183	CMK	CMK is a RSK2 kinase inhibitor which exhibits similar potency but less chemical stability compared with FMK.
M14182	BIX 02565	BIX 02565 is a potent ribosomal S6 kinase 2 (RSK2) inhibitor with IC50 of 1.1 nM.
M4864	LY2584702 Tosylate	LY2584702 Tosylate is a selective, ATP-competitive p70S6K inhibitor with IC50 of 4 nM.
M4830	LY2584702	LY2584702 is a selective, ATP-competitive p70 S6 kinase inhibitor with IC50 of 4 nM.
M3200	SL 0101-1	SL-0101-1 is a selective p90 RSK inhibitor for RSK2 with IC50 of 89 nM.
M2710	FMK	FMK is a potent and selective inhibitor of p90 ribosomal protein S6 kinaseRSK2 (wt) with IC50 of 15 nM, >600- and 200-fold selectivity for RSK2 than the C436V and T493M mutants.
M2271	PF-4708671	PF-4708671 is a novel cell-permeable inhibitor of S6K1 with Ki/IC50 value of 20 nM/160 nM.
M1948	BI-D1870	BI-D1870 is a small molecule specific inhibitor of the p90 RSK (ribosomal S6 kinase) with an IC50 of 10-30 nM.