Cat.No. | Name | Information |
---|---|---|
M19285 | Vitamin A | Vitamin A (Retinol) is a naturally occuring fat-soluble vitamin that is important for normal vision, the immune system, and reproduction. It also plays roles in normal functioning of heart, lungs, kidneys, and other organs. |
M2241 | Adapalene | Adapalene is a third-generation topical retinoid, it is a potent RAR agonist, with AC50 values of 2.3 nM, 9.3 nM, and 22 nM for RARβ, RARγ, RARα, respectively. Adapalene also inhibits the enzymatic activity of GOT1 in a non-competitive manner. |
M14529 | Talarozole | Talarozole (R115866) is an oral systemic all-trans retinoic acid metabolism blocking agent (RAMBA) which increases intracellular levels of endogenous all-trans retinoic acid (RA). |
M14524 | Tarenflurbil | Tarenflurbil ((R)-Flurbiprofen) is the R-enantiomer of the racemate NSAID Flurbiprofen, Tarenflurbil ((R)-Flurbiprofen) inhibits the binding of [3H]9-cis-RA to RXRα LBD with IC50 of 75 μM. |
M11052 | Bigelovin | Bigelovin is a sesquiterpene lactone isolated from sea lilies and is an α agonist of the selective retinoid X receptor α. Bigelovin exerts antitumor activity by inducing apoptosis and autophagy. Bigelovin regulates the mTOR signal path by suppressing the generation of ROS. |
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