| Cat.No. | Name | Information |
|---|---|---|
| M19285 | Vitamin A | Vitamin A (Retinol) is a naturally occuring fat-soluble vitamin that is important for normal vision, the immune system, and reproduction. It also plays roles in normal functioning of heart, lungs, kidneys, and other organs. |
| M2241 | Adapalene | Adapalene is a third-generation topical retinoid, it is a potent RAR agonist, with AC50 values of 2.3 nM, 9.3 nM, and 22 nM for RARβ, RARγ, RARα, respectively. Adapalene also inhibits the enzymatic activity of GOT1 in a non-competitive manner. |
| M6573 | CD 2665 | CD 2665 is a selective RARβ/γ antagonist. |
| M6521 | BMS 753 | BMS 753 is a rARα-selective agonist. |
| M6416 | AGN 193109 | AGN 193109 is a high affinity pan-RAR antagonist. |
| M6155 | AR7 | AR7 is a retinoic acid receptor α (RARα) antagonist, it specifically activates chaperone-mediated-autophagy (CMA) activity without affecting macroautophagy. |
| M5455 | Bexarotene | Bexarotene (LGD1069) is a retinoid specifically selective for retinoid X receptors, used as an oral antineoplastic agent in the treatment of cutaneous T-cell lymphoma. |
| M4774 | 11-hydroxy-sugiol | 11-hydroxy-sugiol |
| M3973 | Tazarotene | Tazarotene (AGN 190168) is a new member of the acetylenic class of RARβ/γ selective retinoids which is approved to treat a variety of skin diseases, exhibits an anti-proliferative effect in human basal cell carcinoma (BCC) by triggering caspase-dependent apoptosis. |
| M3150 | Fenretinide | Fenretinide (4-HPR) is a synthetic retinoid deriverative. Fenretinide is shown to exhibit binding to the retinoic acid receptors (RAR) at concentrations necessary to induce cell death. |
| M3094 | TTNPB | TTNPB (Arotinoid Acid) is a potent RAR agonist, and inhibits binding of [3H]tRA with IC50 of 5.1 nM, 4.5 nM, and 9.3 nM for human RARα, β, and γ, respectively. |
| M3049 | Tamibarotene | Tamibarotene is a synthetic retinoic acid receptor (RAR) agonist with high specificity for RARα and RARβ over RARγ. |
| M1961 | Acitretin (Ro 10-1670) | Acitretin (Ro 10-1670) is a second-generation retinoid. |
| M43837 | KCL-286 | KCL-286 is an orally active retinoic acid receptor-beta (RAR-beta) agonist for studies related to spinal cord injury. |
| M42602 | XS-060 | XS-060 is a potent anticancer agent and RXRα antagonist. |
| M42601 | BPA-B9 | BPA-B9 is a RXRα ligand and antagonist targeting the pRXRα-PLK1 interaction. |
| M42600 | ER 50891 quarterhydrate | ER 50891 quarterhydrate is a potent antagonist of retinoic acid receptor α(RARα). |
| M42599 | 4-Hydroxyretinoic acid | 4-Hydroxyretinoic acid (4-HRA) is a naturally occurring retinoid derivative with diverse biological effects. |
| M42598 | K-80001 | K-80001 is an RXRα-binder and COX-1/2 inhibitor, with IC50s of with an IC50 of 82.9μM, 3.4μM, 1.2μM for RXRα, COX-1 and COX-2, respectively. |
| M42597 | HX630 | HX630 is a potent retinoic acid X receptor (RXR) agonist, can induce apoptosis, has anti-tumor effect, and can be used in Cushing's disease research. |
| M21366 | AGN194204 | AGN194204 (IRX4204) is inactive against RAR and is an orally active and selective RXR agonist with Kd values of 0.4 nM, 3.6 nM and 3.8 nM for RXRα, RXRβ and RXRγ, respectively, and EC50s of 0.2 nM, 0.8 nM and 0.08 nM. AGN194204 has anti-inflammatory and anti-cancer effects. |
| M18161 | 16α-Hydroxytrametenolic acid | 16α-Hydroxytrametenolic acid |
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