|M7559||ON1231320||ON1231320, also known as GBO-006, is a Polo-like kinase 2 (PLK2) inhibitor. In vitro testing revealed that ON1231320 is a selective inhibitor of PLK2 with no inhibitory activity against PLK1, PLK3 and PLK4.|
|M3293||HMN-214||HMN-214 is a procompound of HMN-176, which alters the cellular spatial orientation of Plk1.|
|M3198||TAK-960||TAK-960 is a novel, potent and selective Plk1 inhibitor with IC50 of 8 nM.|
|M2983||Ro3280||RO3280 is a potent, highly selective inhibitor of Polo-like kinase 1 (PLK1) with IC50 of 3 nM.|
|M2860||MLN0905||MLN0905 is a potent inhibitor of PLK1 with IC50 of 2 nM.|
|M2741||GW843682X||GW 843682X is a PLK inhibitor for PLK1 and PLK3 with IC50 of 2.2 nM and 9.1 nM, respectively.|
|M2211||Rigosertib||Rigosertib is a dual non-ATP inhibitor of polo-like kinase 1 (Plk1) and phosphoinositide 3-kinase pathways (PI3K).|
|M1719||GSK461364||GSK461364 is a potent and selective small molecule inhibitor of Polo-like kinase 1 (PLK1) with a Ki of 2.2 nM.|
|M1678||BI 6727||BI 6727 (Volasertib) is a small highly potent Polo-like kinase inhibitor (Plk1) with an IC50 of 0 .87 nM.|
|M1672||BI 2536||BI 2536 is a novel, highly selective, potent inhibitor of Polo-like kinase 1 (Plk1) with an IC50 of 0.83 nM.|
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