Catalog

PLK Polo-like kinase

Inhibitors

Cat.No.	Name	Information
M7559	ON1231320	ON1231320, also known as GBO-006, is a Polo-like kinase 2 (PLK2) inhibitor. In vitro testing revealed that ON1231320 is a selective inhibitor of PLK2 with no inhibitory activity against PLK1, PLK3 and PLK4.
M3293	HMN-214	HMN-214 is a procompound of HMN-176, which alters the cellular spatial orientation of Plk1.
M3198	TAK-960	TAK-960 is a novel, potent and selective Plk1 inhibitor with IC50 of 8 nM.
M2983	Ro3280	RO3280 is a potent, highly selective inhibitor of Polo-like kinase 1 (PLK1) with IC50 of 3 nM.
M2860	MLN0905	MLN0905 is a potent inhibitor of PLK1 with IC50 of 2 nM.
M2741	GW843682X	GW 843682X is a PLK inhibitor for PLK1 and PLK3 with IC50 of 2.2 nM and 9.1 nM, respectively.
M2211	Rigosertib	Rigosertib is a dual non-ATP inhibitor of polo-like kinase 1 (Plk1) and phosphoinositide 3-kinase pathways (PI3K).
M1719	GSK461364	GSK461364 is a potent and selective small molecule inhibitor of Polo-like kinase 1 (PLK1) with a Ki of 2.2 nM.
M1678	BI 6727	BI 6727 (Volasertib) is a small highly potent Polo-like kinase inhibitor (Plk1) with an IC50 of 0 .87 nM.
M1672	BI 2536	BI 2536 is a novel, highly selective, potent inhibitor of Polo-like kinase 1 (Plk1) with an IC50 of 0.83 nM.