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MLN0905

Cat. No. M2860
MLN0905 Structure
Size Price Availability Quantity
2mg USD 120 In stock
5mg USD 160 In stock
25mg USD 460 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

MLN0905 is a potent inhibitor of PLK1 with IC50 of 2 nM.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 486.56
Formula C24H25F3N6S
CAS Number 1228960-69-7
Purity >99%
Solubility DMSO 80 mg/mL
Storage at -20°C
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Ro3280

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GW843682X

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: MLN0905 supplier, PLK, inhibitors

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