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Parasite Antiparasitics

Cat.No.  Name Information
M41210 Carpaine Carpaine is an alkaloid isolated from Carica papaya Linn with anti-thrombocytopenic activity, exhibits potent activity in sustaining platelet counts with no acute toxicity.
M40537 Lotilaner Lotilaner is a first-in-class, highly selective inhibitor of gamma-aminobutyric acid (GABA) gated chloride channels (GABACls) against mites. It has antiparasitic activity with an IC50 value of 23.84 nM against the Drosophila GABA receptor and can be used in studies related to helminth mite blepharitis.
M31124 Quinine dihydrochloride Quinine dihydrochloride is an orally active alkaloid extracted from cinchona bark and can be used in anti-malarial studies. Quinine dihydrochloride is also a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100 mV with an IC50 of 169 μM.
M30887 λ-Cyhalothrin λ-Cyhalothrin is a high efficiency, broad-spectrum type II synthetic pyrethroid insecticide containing α-cyano group. λ-Cyhalothrin is used to control a wide range of pests in a variety of applications. λ-Cyhalothrin is a neurotoxin that targets sodium channels in the membranes of neurons in the central nervous system.
M30846 Primaquine  Primaquine is a potent antimalaria agent and a potent gametocytocide in falciparum malaria. Primaquine prevents relapse in vivax and ovale malaria.
M27605 Pentamidine Pentamidine (MP-601205) is an antimicrobial agent and interferes with DNA biosynthetics. Pentamidine inhibits parasite Leishmania infantum with an IC50 of 2.5 μM. Pentamidine is a potent and selective protein tyrosine phosphatases (PTPases) and phosphatase of regenerating liver (PRL) inhibitor. Pentamidine has the potential for Gambian trypanosomiasis, antimony-resistant leishmaniasis, and Pneumocystis carinii pneumonia treatment. Antitumor and antibacterial activities.
M22413 Allopurinol riboside Allopurinol riboside
M21759 Arterolane Arterolane
M21718 PI-55 PI-55 is a specific cytokinin receptor inhibitor. PI-55 is structurally related to 6-benzylaminopurine (BAP) and was shown to inhibit competitively BAP binding on Arabidopsis-specific receptors CRE1/AHK4 and AHK3.
M21475 Ganaplacide phosphate Ganaplacide (KAF156) phosphate is a first-in-class antimalarial compound with oral activity. Ganaplacide hydrochloride is active on a variety of plasmodium parasites, including drug-resistant parasites.
M20484 Carbaryl Carbaryl is a carbamate insecticide and parasiticide and also a potent anticholinesterase agent belonging to the carbamate group of reversible cholinesterase inhibitors.
M19957 Doramectin Doramectin is a macrocyclic lactone derivative of ivermectin, an anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes. It is used for the treatment and control of internal parasitosis, ticks and mange.
M19952 Sulfalene (SMPZ) Sulfalene(SMPZ)is a cyclic organic chemical used as a versatile synthetic intermediate.
M19880 Moxidectin Moxidectin is a potent, broad-spectrum endectocide with activity against a wide range of nematodes, insects and acari.
M19429 Quinine Quinine is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100 mV with an IC50 of 169 μM.
M13491 Amodiaquine dihydrochloride Amodiaquine dihydrochloride (Amodiaquin dihydrochloride), a 4-aminoquinoline class of antimalarial agent, is a potent and orally active histamine N-methyltransferase inhibitor with a Ki of 18.6 nM.
M11545 Dichlorophen Dichlorophen (DDM) is a tapeworm repellent compound. Dichlorophen is an antimicrobial agent that is active against tapeworms, protozoa, fungi and bacteria.
M11413 Antimony Potassium
M10987 DL-Methionine DL-Methionine is an essential amino acid containing sulfur that has antioxidant stress defenses. DL-Methionine can be used as a natural feed for animals and can also kill potato golden nematodes (H. rostochiensis) on potatoes.
M10694 INE963 INE963 is an oral, single-dose, fast-acting blood-stage antimalarial candidate with an EC50 value of 3-6 nM.




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