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Parasite Antiparasitics

Cat.No.  Name Information
M5571 Diclazuril Diclazuril is an anti-coccidial drug.
M5556 DEET DEET is the most common active ingredient in insect repellents. It is intended to provide protection against mosquitoes, ticks, fleas, chiggers, leeches, and many other biting insects.
M5539 Crotamiton Crotamiton is a drug that is used both as a scabicidal (for treating scabies) and as a general antipruritic. It is a prescription lotion based medicine that is applied to the whole body to get rid of the scabies parasite.
M5529 Clofentezine Clofentezine, a growth inhibitor, has sublethal effects on life-table parameters of Tetranychus urticae Koch females.
M5452 Bephenium hydroxynaphthoate Bephenium hydroxynaphthoate is an anthelmintic agent formerly used in the treatment of hookworm infections and ascariasis; B-type AChR activator.
M5451 Benzyl benzoate Benzyl benzoate is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei.
M5421 Artemotil Artemotil (β-Arteether) is a fast acting blood schizonticide specifically indicated for the treatment of chloroquine-resistant Plasmodium falciparum malaria and cerebral malaria cases.
M5419 Antimonyl potassium tartrate trihydrate Antimony potassium tartrate trihydrate is a powerful emetic, also used in the treatment of schistosomiasis and leishmaniasis.
M5132 Quinacrine Dihydrochloride Dihydrate Quinacrine Hydrochloride Hydrate (Mepacrine Hydrochloride) is an antimalarial that has anti-tumor effects in vivo and in vitro. Quinacrine hydrochloride hydrate inhibits NF-κB, activates p53 signal transduction and induces apoptosis in tumor cells.
M5021 Dinotefuran Dinotefuran is an insecticide of the neonicotinoid class, its mechanism of action involves disruption of the insect's nervous system by inhibiting nicotinic acetylcholine receptors.
M4910 Secnidazole Secnidazole (flagellate) is a nitroimidazoles anti - infective compound.
M4892 GNF179 GNF179 is an optimized 8,8-dimethyl IP analog that exhibited the potency(4.8 nM against the multidrug resistant strain W2).
M4886 Selamectin Selamectin is an antiparasitic agent and insect repellent that activates glutamate-gated chloride channels in neurons and pharyngeal muscles to prevent filariasis, lymphatic filariasis and nematode infection. Selamectin is also an effective p-glycoprotein substrate and inhibitor with IC50 of 120 nM.
M4757 1,2,3,4,6-pentagalloylglucose 1,2,3,4,6-pentagalloylglucose
M4669 Tuberostemonine Tuberostemonine is an alkaloid, an antimalarial that targets plasmodium falciparum ferridogen-NADP + reductase (pfFNR).
M4645 Filixic-acid-ABA Filixic-acid-ABA
M4583 (-)-Maackiain Maackiain (DL-Maackiain) was separated from Maackia amurensis Rupr. Et Maxim. Maackiain (DL-Maackiain) is a larval insecticide against Aedes aegypti with a LD50 of 21.95 μg/ mL. Maackiain (DL-Maackiain) induces DNA fragmentation into oligonucleosome size fragments, similar to apoptotic characteristics such as HL-60 cells.
M4425 3-Butylidenephthalide 3-butylidenephthalide (i.e. 3-butylidenephthalide) is a phthalic anhydride derivative identified from Ligusticum chuanxiong Hort. It has insecticidal activity (LC50 value of 1.56 mg/g for Spodoptera Litura Spodoptera).
M4285 Harpgide Harpgide is a class of iridoid glycoside isolated from Scrophularia ningpoensis and has antiparasitic activity, which exhibits good in vitro trypanocidal activities against African trypanosomes (T.b. rhodesiense) with an IC50 of 21 μg/mL.
M3990 Betulonic acid Betulinic acid (Betulinic acid) is an inhibitor of eukaryotic cell topoisomerase I with IC50 value of 5 μM. It has anti-inflammatory, anti-malaria, anti-AIDS and anti-tumor activities. Betulinic acid is also a new nF-KB agonist.




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