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Benzyl benzoate

Cat. No. M5451
Benzyl benzoate Structure
Synonym:

Ascabiol, Novoscabin, Scabitox, Benzoic acid benzyl ester

Size Price Availability Quantity
1g USD 40  USD40 In stock
5g USD 60  USD60 In stock
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Quality Control & Documentation
Biological Activity

Benzyl benzoate is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei.

Chemical Information
Molecular Weight 212.24
Formula C14H12O2
CAS Number 120-51-4
Form Liquid
Solubility (25°C) 10mM in DMSO
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Chedgy RJ, et al. Phytochemistry. Functional characterization of two acyltransferases from Populus trichocarpa capable of synthesizing benzyl benzoate and salicyl benzoate, potential intermediates in salicinoid phenolic glycoside biosynthesis.

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Keywords: Benzyl benzoate, Ascabiol, Novoscabin, Scabitox, Benzoic acid benzyl ester supplier, Parasite, inhibitors, activators


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