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Dichlorophen

Cat. No. M11545
Dichlorophen Structure
Synonym:

Dichlorophene; Bis(5-chloro-2-hydroxyphenyl)methane; DDM

Size Price Availability Quantity
500mg USD 45  USD45 In stock
1g USD 60  USD60 In stock
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Quality Control & Documentation
Biological Activity

Dichlorophen (DDM) is a tapeworm repellent compound. Dichlorophen is an antimicrobial agent that is active against tapeworms, protozoa, fungi and bacteria.

Chemical Information
Molecular Weight 269.12
Formula C13H10Cl2O2
CAS Number 97-23-4
Form Solid
Solubility (25°C) DMSO ≥ 40 mg/mL
Storage RT
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Tiffany H Khaw, et al. ACS Omega. Identification of Bithionol, Dichlorophen, and Miconazole as Antibacterial Agents against Acinetobacter calcoaceticus

[2] Julia Fabbri, et al. Parasitology. Drug repurposing for the treatment of alveolar echinococcosis: in vitro and in vivo effects of silica nanoparticles modified with dichlorophen

[3] Abraham Vidal-Limon, et al. Bioconjug Chem. Enhanced Degradation of Pesticide Dichlorophen by Laccase Immobilized on Nanoporous Materials: A Cytotoxic and Molecular Simulation Investigation

[4] Huanhuan Shi, et al. J Hazard Mater. Laccase-catalyzed removal of the antimicrobials chlorophene and dichlorophen from water: Reaction kinetics, pathway and toxicity evaluation

[5] J Langrand, et al. Clin Toxicol (Phila). A life-threatening dichlorophen poisoning case: clinical features and kinetics study

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Keywords: Dichlorophen, Dichlorophene; Bis(5-chloro-2-hydroxyphenyl)methane; DDM supplier, Parasite, inhibitors, activators


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